201856-57-7

• 常用中文名：(3R,4S)-3-(1-乙氧乙氧基)-2-氧-4-苯基-吖丁啶羧酸叔丁基酯
• 常用英文名：(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
• CAS号：201856-57-7
• 分子式：C₁₈H₂₅NO₅
• 分子量：335.395
• 发布时间：2019-01-07 09:47:14
• 更新时间：2026-08-02 18:45:20

名称

• 中文名: (3R,4S)-3-(1-乙氧乙氧基)-2-氧-4-苯基-吖丁啶羧酸叔丁基酯
• 英文名: tert-butyl (3R,4S)-3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
• 中文别名: 多西他赛手性侧链(3R,4S)-3-(1-乙氧乙氧基)-2-氧-4-苯基-吖丁啶羧酸叔丁基酯; (3R,4S)-1-叔丁氧基羰基-3-(1-乙氧基乙氧基)-4-苯基-2-氮杂环丁酮; 多西他赛杂质54; (3R, 4S)-1-叔丁氧基羰基-3-(1-乙氧基乙氧基)-4-苯基-2-氮杂环丁酮; (3R,4S)-3-(1-乙氧基乙氧基)-2-氧代-4-苯基氮杂环丁烷-1-羧酸叔丁酯; (3R,4S)-1-叔丁氧基羰基-3-(2-乙氧乙氧基)-4-苯基-2-丙内酰胺; (3R,4S)-1-叔丁氧羰基-3-(1-乙氧乙氧基)-4-苯基-2-丙内酰胺
• 英文别名: (3r,4s)-tert-butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-cboxylate; (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecboxylic Acid 1,1-DiMethylethyl Ester; Docetaxel Intermediate I; (3R,4S)-1-t-butoxycbonyl-3-(2-ethoxyethoxyl)-4-phenyl-2-azetidinone; (3R,4S)-1-AZETIDINECBOXYLIC ACID-3-(2-ETHOXYETHOXY)-4-PHENYL-2-PHENYL-AZETIDIONE; 3-(1-ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecboxylic acid tert-butyl ester; 1-Azetidinecboxylic acid, 3-(1-ethoxyethoxy)-2-oxo-4-phenyl-, 1,1-dimethylethyl ester, (3R,4S); Docetaxel Impurity 54; (3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-Boc-2-azetidinone; SIDE CHAINS OF DOCETAXEL-1; Docetaxel Impurity 48; 3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecboxylic acid 1,1-dimethylethyl ester; 2-Methyl-2-propanyl (3R,4S)-3-(1-ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylate; (3R, 4S) -1-tert butoxycbonyl-3- (2-ethoxyethoxy) -4-phenyl-2-propanolam; tert-butyl (3R,4S)-3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-cboxylate; (1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecboxylic acid 1,1-dimethyl ethyl ester; (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidin

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 459.6±45.0 °C at 760 mmHg
• 分子式: C₁₈H₂₅NO₅
• 分子量: 335.395
• 闪点: 231.8±28.7 °C
• 精确质量: 335.173279
• PSA: 65.07000
• LogP: 2.30
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.532
• 储存条件: 2-8°C，干燥

合成路线

24424-99-5 201856-48-6 ~93% 201856-57-7

文献：Ojima, Iwao; Sun, Chung Ming; Zucco, Martine; Park, Young Boon; Duclos, Olivier; Kuduk, Scott Tetrahedron Letters, 1993 , vol. 34, # 26 p. 4149 - 4152

132127-34-5 ~% 201856-57-7

文献：Tetrahedron Letters, , vol. 34, # 26 p. 4149 - 4152

132127-31-2 ~% 201856-57-7

文献：Tetrahedron Letters, , vol. 34, # 26 p. 4149 - 4152

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