4394-04-1

• 常用中文名：甲尼辛
• 常用英文名：2-(2,6-dimethylanilino)pyridine-3-carboxylic acid
• CAS号：4394-04-1
• 分子式：C₁₄H₁₄N₂O₂
• 分子量：242.27300
• 发布时间：2018-09-22 10:38:15
• 更新时间：2024-01-19 00:27:27

名称

• 中文名: 甲尼辛
• 英文名: 2-(2,6-dimethylanilino)pyridine-3-carboxylic acid
• 英文别名: Metanixin; 2-(2',6'-Dimethylphenylamin)-3-pyridincarboxylsaeure; 2-[(2,6-dimethylphenyl)amino]pyridine-3-carboxylic acid; Acido nixilico; 2-(2,6-xylidino)-nicotinic acid; Acidum nixylicum; Metanixine [INN-French]; Metanixino [Spanish]; 2-(2,6-dimethyl-anilino)-nicotinic acid; 2-(2,6-Dimethyl-anilino)-nicotinsaeure; Metanixinum [Latin]; Metanixinum [INN-Latin]; Metanixino [INN-Spanish]; Metanixine [French]; Acide nixylique

物化性质

• 密度: 1.25 g/cm3
• 沸点: 393.972ºC at 760mmHg
• 分子式: C₁₄H₁₄N₂O₂
• 分子量: 242.27300
• 闪点: 192.068ºC
• 精确质量: 242.10600
• PSA: 62.22000
• LogP: 3.21320
• 折射率: 1.646

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QT2999350 CHEMICAL NAME : Nicotinic acid, 2-(2,3-xylidino)- CAS REGISTRY NUMBER : 4394-04-1 BEILSTEIN REFERENCE NO. : 0482454 LAST UPDATED : 199712 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H14-N2-O2 MOLECULAR WEIGHT : 242.30 WISWESSER LINE NOTATION : T6NJ BMR B1 C1& CVQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2300 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 645 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 385 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 280 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967

安全

• 海关编码: 2933399090

合成路线

2942-59-8 87-62-7 ~37% 4394-04-1

文献：Li, Zhenghua; Xiao, Shangyou; Liang, Ronghui; Xia, Zhining Research on Chemical Intermediates, 2012 , vol. 38, # 7 p. 1691 - 1697

上下游产品

上游产品  2
2942-59-8 87-62-7
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89109-28-4

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%