22365-40-8

• 常用中文名：三氟巴占
• 常用英文名：Triflubazam
• CAS号：22365-40-8
• 分子式：C₁₇H₁₃F₃N₂O₂
• 分子量：334.29300
• 发布时间：2018-08-07 04:29:08
• 更新时间：2024-01-16 17:17:13

名称

• 中文名: 三氟巴占
• 英文名: 1-methyl-5-phenyl-7-(trifluoromethyl)-1,5-benzodiazepine-2,4-dione
• 英文别名: Triflubazam; 7-trifluoromethyl-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione; Triflubazam [USAN:INN]; 1-methyl-5-phenyl-7-trifluoromethyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione; Triflubazamum [INN-Latin]; WE 352; ORF-8063; 1-Methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione

物化性质

• 密度: 1.354g/cm3
• 沸点: 599.9ºC at 760mmHg
• 分子式: C₁₇H₁₃F₃N₂O₂
• 分子量: 334.29300
• 闪点: 316.6ºC
• 精确质量: 334.09300
• PSA: 40.62000
• LogP: 3.86660
• 蒸汽压: 2.38E-14mmHg at 25°C
• 折射率: 1.561

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DE9610000 CHEMICAL NAME : 1H-1,5-Benzodiazepine-2,4-(3H,5H)-dione, 1-methyl-5-phenyl-7-trifluoromethyl- CAS REGISTRY NUMBER : 22365-40-8 BEILSTEIN REFERENCE NO. : 0765367 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H13-F3-N2-O2 MOLECULAR WEIGHT : 334.32 WISWESSER LINE NOTATION : T67 GNV JVN IHJ CXFFF G1 KR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 16,1022,1974

安全

• 危险品运输编码: UN 3249
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 2933990090

合成路线

20200-22-0 ~% 22365-40-8

文献：Fader, Lee D.; Bethell, Richard; Bonneau, Pierre; Boes, Michael; Bousquet, Yves; Cordingley, Michael G.; Coulombe, Rene; Deroy, Patrick; Faucher, Anne-Marie; Gagnon, Alexandre; Goudreau, Nathalie; Grand-Maitre, Chantal; Guse, Ingrid; Hucke, Oliver; Kawai, Stephen H.; Lacoste, Jean-Eric; Landry, Serge; Lemke, Christopher T.; Malenfant, Eric; Mason, Stephen; Morin, Sebastien; O'Meara, Jeff; Simoneau, Bruno; Titolo, Steve; Yoakim, Christiane Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 398 - 404

35203-49-7 ~% 22365-40-8

文献：Fader, Lee D.; Bethell, Richard; Bonneau, Pierre; Boes, Michael; Bousquet, Yves; Cordingley, Michael G.; Coulombe, Rene; Deroy, Patrick; Faucher, Anne-Marie; Gagnon, Alexandre; Goudreau, Nathalie; Grand-Maitre, Chantal; Guse, Ingrid; Hucke, Oliver; Kawai, Stephen H.; Lacoste, Jean-Eric; Landry, Serge; Lemke, Christopher T.; Malenfant, Eric; Mason, Stephen; Morin, Sebastien; O'Meara, Jeff; Simoneau, Bruno; Titolo, Steve; Yoakim, Christiane Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 398 - 404

603-33-8 61352-54-3 ~% 22365-40-8

文献：Fader, Lee D.; Bethell, Richard; Bonneau, Pierre; Boes, Michael; Bousquet, Yves; Cordingley, Michael G.; Coulombe, Rene; Deroy, Patrick; Faucher, Anne-Marie; Gagnon, Alexandre; Goudreau, Nathalie; Grand-Maitre, Chantal; Guse, Ingrid; Hucke, Oliver; Kawai, Stephen H.; Lacoste, Jean-Eric; Landry, Serge; Lemke, Christopher T.; Malenfant, Eric; Mason, Stephen; Morin, Sebastien; O'Meara, Jeff; Simoneau, Bruno; Titolo, Steve; Yoakim, Christiane Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 398 - 404

上下游产品

上游产品  4
20200-22-0 35203-49-7 603-33-8 61352-54-3
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%