436-40-8

436-40-8结构式

常用中文名：2,5-Cyclohexadiene-1,4-dione,2,5-bis(1-aziridinyl)-3,6-dipropoxy-
常用英文名：2,5-Cyclohexadiene-1,4-dione,2,5-bis(1-aziridinyl)-3,6-dipropoxy-
CAS号：436-40-8
分子式：C₁₆H₂₂N₂O₄
分子量：306.35700
发布时间：2016-12-08 08:31:48
更新时间：2024-01-30 12:43:35

英文名	2,5-bis(aziridin-1-yl)-3,6-dipropoxycyclohexa-2,5-diene-1,4-dione
英文别名	Bayer E 39 2,5-bis-aziridin-1-yl-3,6-dipropoxy-[1,4]benzoquinone 2,5-Bis-aziridin-1-yl-3,6-dipropoxy-[1,4]benzochinon Cytostaticum Improcuona [INN-Spanish] Zytostatika Inprochonum Inproquonum [INN-Latin] Cytostatika 2.5-Bis-<aziridinyl-(1)>-3.6-di-propyloxy-benzochinon-(1.4) Inproquone E 39 RP 6870

分子式	C₁₆H₂₂N₂O₄
分子量	306.35700
精确质量	306.15800
PSA	58.62000
LogP	0.92160

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK3327000

CHEMICAL NAME :: p-Benzoquinone, 2,5-bis(1-aziridinyl)-3,6-dipropoxy-

CAS REGISTRY NUMBER :: 436-40-8

BEILSTEIN REFERENCE NO. :: 0286633

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C16-H22-N2-O4

MOLECULAR WEIGHT :: 306.40

WISWESSER LINE NOTATION :: T3NTJ A- BL6V DVJ CO3 FO3 E- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4300 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Blood - hemorrhage Nutritional and Gross Metabolic - other changes

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Cells - not otherwise specified

DOSE/DURATION :: 290 nmol/L

REFERENCE :: SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 18,210,1982

海关编码	2933990090

7251-14-1

6819-41-6

436-40-8

文献：Farbenfabr. Bayer Patent: DE943166 , 1954 ; Full Text Show Details Lidaks et al. Latvijas PSR Zinatnu Akademijas Vestis, 1959 , # 1 p. 87,88 Chem.Abstr., 1959 , p. 17991 Full Text Show Details Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

57998-73-9

6819-41-6

436-40-8

488-48-2

436-40-8

文献：Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

118-75-2

436-40-8

文献：Petersen et al. Angewandte Chemie, 1955 , vol. 67, p. 217,219

上游产品 5
7251-14-1 6819-41-6 57998-73-9 488-48-2
118-75-2
下游产品 0

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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