5135-83-1

• 常用中文名：2-dimethylamino-1-(1-ethylindol-3-yl)ethanol
• 常用英文名：2-dimethylamino-1-(1-ethylindol-3-yl)ethanol
• CAS号：5135-83-1
• 分子式：C₁₄H₂₀N₂O
• 分子量：232.32100
• 发布时间：2017-05-07 01:48:00
• 更新时间：2024-01-15 18:24:53

名称

• 英文名: 2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol
• 英文别名: 1-(1-Aethyl-indol-3-yl)-2-dimethylamino-aethanol; 1-(1-ethyl-indol-3-yl)-2-dimethylamino-ethanol

物化性质

• 密度: 1.06g/cm3
• 沸点: 395.7ºC at 760 mmHg
• 分子式: C₁₄H₂₀N₂O
• 分子量: 232.32100
• 闪点: 193.1ºC
• 精确质量: 232.15800
• PSA: 28.40000
• LogP: 2.25620
• 折射率: 1.559

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NL9485600 CHEMICAL NAME : Indole-3-methanol, alpha-((dimethylamino)methyl)-1-ethyl- CAS REGISTRY NUMBER : 5135-83-1 BEILSTEIN REFERENCE NO. : 0192669 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H20-N2-O MOLECULAR WEIGHT : 232.36 WISWESSER LINE NOTATION : T56 BNJ B2 DYQ1N1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 233 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 133 mg/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section Kidney, Ureter, Bladder - urine volume increased REFERENCE : FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963

合成路线

101938-53-8 ~% 5135-83-1

文献：Upjohn Co. Patent: US2825734 , 1955 ;

120-72-9 ~% 5135-83-1

文献：Upjohn Co. Patent: US2825734 , 1955 ;

22980-09-2 ~% 5135-83-1

文献：Upjohn Co. Patent: US2825734 , 1955 ;

29095-44-1 ~% 5135-83-1

文献：Upjohn Co. Patent: US2825734 , 1955 ;

上下游产品

上游产品  3
120-72-9 22980-09-2 29095-44-1
下游产品  0