220499-12-7

• 常用中文名：N-boc-4-羟基甲基 吲哚
• 常用英文名：tert-Butyl 4-(hydroxymethyl)-1H-indole-1-carboxylate
• CAS号：220499-12-7
• 分子式：C₁₄H₁₇NO₃
• 分子量：247.29000
• 发布时间：2018-06-19 22:13:07
• 更新时间：2026-07-03 11:42:59

名称

• 中文名: N-boc-4-羟基甲基 吲哚
• 英文名: tert-butyl 4-(hydroxymethyl)indole-1-carboxylate
• 中文别名: 4-(羟甲基)-1H-吲哚-1-甲酸叔丁酯
• 英文别名: 2-Methyl-2-propanyl 4-(hydroxymethyl)-1H-indole-1-cboxylate; 1-BOC-4-HYDROXYMETHYLINDOLE; N-Boc-4-hydroxymethyl indole; 4-hydroxymethyl-indole-1-carboxylic acid tert-butyl ester; Y8313; 1H-Indole-1-cboxylic acid, 4-(hydroxyMethyl)-, 1,1-diMethylethyl ester; 1-Boc-4-hydrxoymethylindole; tert-butyl 4-(hydroxymethyl)-1H-1-indolecarboxylate; tert-Butyl 4-(hydroxymethyl)-1H-indole-1-cboxylate; tert-butyl 4-(hydroxymethyl)indole-1-cboxylate

物化性质

• 分子式: C₁₄H₁₇NO₃
• 分子量: 247.29000
• 精确质量: 247.12100
• PSA: 51.46000
• LogP: 2.91680

合成路线

220499-11-6 ~95% 220499-12-7

文献：NOVARTIS AG; BERST, Frederic; FURET, Pascal; MARZINZIK, Andreas; STAUFFER, Frederic Patent: WO2011/157793 A1, 2011 ; Location in patent: Page/Page column 46 ; WO 2011/157793 A1

1313237-54-5 ~96% 220499-12-7

文献：NOVARTIS AG; BERST, Frederic; FURET, Pascal; MARZINZIK, Andreas Patent: WO2011/157787 A1, 2011 ; Location in patent: Page/Page column 60 ; WO 2011/157787 A1

39830-66-5 ~% 220499-12-7

文献：NOVARTIS AG; BERST, Frederic; FURET, Pascal; MARZINZIK, Andreas; STAUFFER, Frederic Patent: WO2011/157793 A1, 2011 ; WO 2011/157793 A1

59382-59-1 ~% 220499-12-7

文献：Fauq, Abdul H.; Hong, Feng; Cusack, Bernadette; Tyler, Beth M.; Ping-Pang, Yuan; Richelson, Elliott Tetrahedron Asymmetry, 1998 , vol. 9, # 23 p. 4127 - 4134

1975-50-4 ~% 220499-12-7

文献：Fauq, Abdul H.; Hong, Feng; Cusack, Bernadette; Tyler, Beth M.; Ping-Pang, Yuan; Richelson, Elliott Tetrahedron Asymmetry, 1998 , vol. 9, # 23 p. 4127 - 4134

73816-11-2 ~% 220499-12-7

文献：Fauq, Abdul H.; Hong, Feng; Cusack, Bernadette; Tyler, Beth M.; Ping-Pang, Yuan; Richelson, Elliott Tetrahedron Asymmetry, 1998 , vol. 9, # 23 p. 4127 - 4134

24424-99-5 ~% 220499-12-7

文献：NOVARTIS AG; BERST, Frederic; FURET, Pascal; MARZINZIK, Andreas Patent: WO2011/157787 A1, 2011 ; WO 2011/157787 A1

136669-32-4 ~% 220499-12-7

文献：NOVARTIS AG; BERST, Frederic; FURET, Pascal; MARZINZIK, Andreas Patent: WO2011/157787 A1, 2011 ; WO 2011/157787 A1

上下游产品

上游产品  7
220499-11-6 39830-66-5 59382-59-1 1975-50-4
73816-11-2 24424-99-5 136669-32-4
下游产品  1
220499-13-8