937174-74-8

• 常用中文名：(S)-3-(((2-(4-氨基-1,2,5-恶二唑-3-基)-4-氯-1-乙基-1H-咪唑
• 常用英文名：2-Methyl-2-propanyl 3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chlor o-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinec arboxylate
• CAS号：937174-74-8
• 分子式：C₂₁H₂₈ClN₇O₄
• 分子量：477.94500
• 发布时间：2016-10-04 11:35:48
• 更新时间：2026-07-01 10:59:06

名称

• 中文名: (S)-3-(((2-(4-氨基-1,2,5-恶二唑-3-基)-4-氯-1-乙基-1H-咪唑
• 英文名: 2-Methyl-2-propanyl 3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chlor o-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinec arboxylate
• 中文别名: (S) - 3 - (((2-(4-氨基-1,2,5-恶二唑-3-基)-4-氯-1-乙基-1H-咪唑; (S)-3-(((2-(4-氨基-1,2,5-噁二唑-3-基)-4-氯-1-乙基-1H-咪唑并[4,5-C]吡啶-7-基)氧基)甲基)哌啶-1-甲酸叔丁酯
• 英文别名: 1,1-dimethylethyl (3S)-3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinecarboxylate; 1,1-dimethylethyl 3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinecarboxylate; 1,1-dimethylethyl (3S)-3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-4-(3-hydroxy-3-methyl-1-butyn-1-yl)-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinecarboxylate; (S)-tert-butyl 3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-iMidazo[4,5-c]pyridin-7-yloxy)Methyl)piperidine-1-cboxylate; 1,1-dimethylethyl 3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-4-(3-hydroxy-3-methyl-1-butyn-1-yl)-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinecarboxylate; 1,1-dimethylethyl 2-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1-Piperidinecboxylic acid, 3-[[[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy]methyl]-, 1,1-dimethylethyl ester, (3S); 2-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid,1,1-dimethylethyl ester

物化性质

• 分子式: C₂₁H₂₈ClN₇O₄
• 分子量: 477.94500
• 精确质量: 477.18900
• PSA: 134.42000
• LogP: 4.28180

合成路线

842149-46-6 158406-99-6 ~84% 937174-74-8

文献：Heerding, Dirk A.; Rhodes, Nelson; Leber, Jack D.; Clark, Tammy J.; Keenan, Richard M.; Lafrance, Louis V.; Li, Mei; Safonov, Igor G.; Takata, Dennis T.; Venslavsky, Joseph W.; Yamashita, Dennis S.; Choudhry, Anthony E.; Copeland, Robert A.; Lai, Zhihong; Schaber, Michael D.; Tummino, Peter J.; Strum, Susan L.; Wood, Edgar R.; Duckett, Derek R.; Eberwein, Derek; Knick, Victoria B.; Lansing, Timothy J.; McConnell, Randy T.; Zhang, ShuYun; Minthorn, Elisabeth A.; Concha, Nestor O.; Warren, Gregory L.; Kumar, Rakesh Journal of Medicinal Chemistry, 2008 , vol. 51, # 18 p. 5663 - 5679

上下游产品

上游产品  2
842149-46-6 158406-99-6
下游产品  1
937174-75-9