122027-54-7

• 常用中文名：Pyridine, 3-(2-(1H-imidazol-4-yl)-1-phenylethyl)-
• 常用英文名：Pyridine, 3-(2-(1H-imidazol-4-yl)-1-phenylethyl)-
• CAS号：122027-54-7
• 分子式：C₁₆H₁₅N₃
• 分子量：249.31000
• 发布时间：2016-05-02 12:38:08
• 更新时间：2024-01-22 07:22:20

名称

• 英文名: 3-[2-(1H-Imidazol-5-yl)-1-phenylethyl]pyridine

物化性质

• 密度: 1.178g/cm3
• 沸点: 440.5ºC at 760mmHg
• 分子式: C₁₆H₁₅N₃
• 分子量: 249.31000
• 闪点: 199.9ºC
• 精确质量: 249.12700
• PSA: 41.57000
• LogP: 3.17930
• 蒸汽压: 1.52E-07mmHg at 25°C
• 折射率: 1.63

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UT4396755 CHEMICAL NAME : Pyridine, 3-(2-(1H-imidazol-4-yl)-1-phenylethyl)- CAS REGISTRY NUMBER : 122027-54-7 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C16-H15-N3 MOLECULAR WEIGHT : 249.34 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 175 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 25,557,1990

合成路线

620-95-1 ~% 122027-54-7

文献：G. D. Searle and Co. Patent: US4882343 A1, 1989 ;

122027-51-4 ~% 122027-54-7

文献：Cordi; Snyers; Giraud-Mangin; Van der Maesen; Van Hoeck; Beuze; Ellens; Napora; Gillet; Gorissen; Calderon; Remacle; Janssens de Varebeke; Van Dorsser; Roba European Journal of Medicinal Chemistry, 1990 , vol. 25, # 7 p. 557 - 568