379230-38-3

• 常用中文名：N-(5-氯苯并[d][1,3]二氧代l-4-基)-7-氟-5-((四氢-2H-吡喃-4-基)氧基)喹唑啉-4-胺
• 常用英文名：N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE
• CAS号：379230-38-3
• 分子式：C₂₀H₁₇ClFN₃O₄
• 分子量：417.818
• 发布时间：2018-12-29 19:37:09
• 更新时间：2024-01-17 09:46:08

名称

• 中文名: N-(5-氯苯并[d][1,3]二氧代l-4-基)-7-氟-5-((四氢-2H-吡喃-4-基)氧基)喹唑啉-4-胺
• 英文名: N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(oxan-4-yloxy)quinazolin-4-amine
• 英文别名: 4-Quinazolinamine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-[(tetrahydro-2H-pyran-4-yl)oxy]-; N-(5-Chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(tetrahydro-2H-pyran-4-yloxy)-4-quinazolinamine; N-(5-Chlorobenzo[d][1,3]dioxol-4-yl)-7-fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-amine; 7-fluoro-N-(5-chloro-1,3-benzodioxol-4-yl)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine; 4-(6-chloro-2,3-methylenedioxyanilino)-7-fluoro-5-tetrahydropyran-4-yloxyquinazoline; QC-8392

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 525.2±50.0 °C at 760 mmHg
• 分子式: C₂₀H₁₇ClFN₃O₄
• 分子量: 417.818
• 闪点: 271.5±30.1 °C
• 精确质量: 417.089172
• PSA: 74.73000
• LogP: 3.50
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.674

安全

• 海关编码: 2934999090

合成路线

2081-44-9 893428-69-8 ~81% 379230-38-3

文献：Raw, Steven A.; Taylor, Brian A.; Tomasi, Simone Organic Process Research and Development, 2011 , vol. 15, # 3 p. 688 - 692

2081-44-9 893428-68-7 ~77% 379230-38-3

文献：Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093

893428-68-7 ~% 379230-38-3

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64217 A2, 2006 ; Location in patent: Page/Page column 57 ; WO 2006/064217 A2

379228-55-4 379228-45-2 ~% 379230-38-3

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64217 A2, 2006 ; Location in patent: Page/Page column 56-57 ; WO 2006/064217 A2

379228-58-7 ~% 379230-38-3

文献：Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093

791602-75-0 ~% 379230-38-3

文献：Raw, Steven A.; Taylor, Brian A.; Tomasi, Simone Organic Process Research and Development, 2011 , vol. 15, # 3 p. 688 - 692

379228-45-2 ~% 379230-38-3

文献：Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093

上下游产品

上游产品  5
2081-44-9 379228-55-4 379228-45-2 379228-58-7
791602-75-0
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%