159874-20-1

• 常用中文名：1-CBZ-4-BOC-氨基哌啶
• 常用英文名：1-BOC-4-CBZ-AMINO-PIPERIDINE
• CAS号：159874-20-1
• 分子式：C₁₈H₂₆N₂O₄
• 分子量：334.410
• 发布时间：2018-10-15 13:54:23
• 更新时间：2024-01-09 20:48:05

名称

• 中文名: 4-(叔丁氧基羰基氨基)哌啶-1-羧酸苄酯
• 英文名: Benzyl 4-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate
• 中文别名: 1-苄氧羰基-4-叔丁氧羰基氨基哌啶
• 英文别名: 1-Piperidinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester; 1-BOC-4-CBZ-AMINO-PIPERIDINE; benzyl 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl 4-{[(benzyloxy)carbonyl]amino}-1-piperidinecarboxylate; tert-Butyl 4-{[(benzyloxy)carbonyl]amino}piperidine-1-carboxylate; Benzyl 4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-1-piperidinecarboxylate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 471.9±44.0 °C at 760 mmHg
• 分子式: C₁₈H₂₆N₂O₄
• 分子量: 334.410
• 闪点: 239.2±28.4 °C
• 精确质量: 334.189270
• PSA: 71.36000
• LogP: 3.06
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.546
• 储存条件: 2-8℃，干燥

安全

• 海关编码: 2933399090

合成路线

501-53-1 73874-95-0 ~87% 159874-20-1

文献：MERCK and CO., INC. Patent: WO2009/91856 A2, 2009 ; Location in patent: Page/Page column 63 ; WO 2009/091856 A2

13139-17-8 ~% 159874-20-1

文献：Zeneca Limited Patent: US5559131 A1, 1996 ; US 5559131 A

10314-98-4 ~% 159874-20-1

文献：Finke, Paul E.; Oates, Bryan; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Schleif, William A.; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 18 p. 2475 - 2479

501-53-1 ~% 159874-20-1

文献：Finke, Paul E.; Oates, Bryan; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Schleif, William A.; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 18 p. 2475 - 2479

10314-99-5 ~% 159874-20-1

文献：Finke, Paul E.; Oates, Bryan; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Schleif, William A.; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 18 p. 2475 - 2479

220394-91-2 75-65-0 ~% 159874-20-1

文献：Finke, Paul E.; Oates, Bryan; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Schleif, William A.; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 18 p. 2475 - 2479

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%