181178-24-5

• 常用中文名：3-(2-氨基乙基)-5-(1-吡咯烷磺酰基甲基)吲哚
• 常用英文名：Didesmethyl Almotriptan
• CAS号：181178-24-5
• 分子式：C₁₅H₂₁N₃O₂S
• 分子量：307.41100
• 发布时间：2019-01-01 19:32:05
• 更新时间：2026-08-02 17:30:54

名称

• 中文名: 3-(2-氨基乙基)-5-(1-吡咯烷磺酰基甲基)吲哚
• 英文名: Didesmethyl Almotriptan
• 中文别名: 阿莫曲坦N,N-二甲基杂质苹果酸盐; 阿莫曲坦 N,N-二去甲基苹果酸盐杂质; 二去甲基阿莫曲坦; 2-{5-[(吡咯烷-1-磺酰)甲基]-1H-吲哚-3-基}乙烷-1-胺; 阿莫曲坦相关化合物B
• 英文别名: 5-[(1-Pyrrolidinylsulfonyl)Methyl]-1H-indole-3-ethanaMine; 2-(5-((Pyrrolidin-1-yl-sulfonyl)methyl)-1H-indol-3-yl)ethanamine; Almotriptan RC B; 1H-Indole-3-ethanamine, 5-[(1-pyrrolidinylsulfonyl)methyl]; 2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine; DidesMethyl AlMotriptan; Almotriptan Related Compound B (Almotriptan Didesmethyl Impurity); Almotriptan Impurity 2; Almotriptan N,N-Didesmethyl; 1-[[3-(2-AMinoethyl)-5-indolyl]Methanesulfonyl]pyrrolidine; Almotriptan Impurity 2（Almotriptan Related Compound B）; Almotriptan Related Compound B; 1-[[[3-(2-AMinoethyl)-1H-indol-5-yl]Methyl]sulfonyl]pyrrolidine; AlmotriptanN,N-Didesmethyl Impurity Malate

物化性质

• 密度: 1.34±0.1 g/cm3(Predicted)
• 沸点: 552.2±60.0 °C(Predicted)
• 分子式: C₁₅H₂₁N₃O₂S
• 分子量: 307.41100
• 精确质量: 307.13500
• PSA: 87.57000
• LogP: 3.31370
• 储存条件: 2-8°C， 密封， 干燥

合成路线

1018676-03-3 ~% 181178-24-5

文献：MSN LABORATORIES LIMITED; SATYANARAYANA REDDY, Manne; ESWARAIAH, Sajja; SAHADEVA REDDY, Maramreddy; SATYANARAYANA, Komati Patent: WO2010/113183 A2, 2010 ; Location in patent: Page/Page column 20-21 ;