196394-48-6

• 常用中文名：(2S,4S)-1-(叔丁氧羰基)-4-甲基焦谷氨酸甲酯
• 常用英文名：METHYL (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-METHYLPYROGLUTAMATE
• CAS号：196394-48-6
• 分子式：C₁₂H₁₉NO₅
• 分子量：257.28300
• 发布时间：2017-10-31 21:56:39
• 更新时间：2026-09-22 08:10:26

名称

• 中文名: (2S,4S)-1-(叔丁氧羰基)-4-甲基焦谷氨酸甲酯
• 英文名: 1-O-tert-butyl 2-O-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate
• 中文别名: 1-(叔丁基)2-甲基(2S,4S)-4-甲基-5-氧代吡咯烷-1,2-二羧酸酯; 奈诺沙星杂质42; 奈若沙星杂质N04-002; 奈若沙星杂质02
• 英文别名: Nemonoxacin Impurity 42; (2S,4S)-1-(1,1-dimethylethyl)-4-methyl-5-oxo-pyrrolidine-1,2-dicarboxylic acid 2-methyl ester; (2S,4S)-1-tert-butyl 2-methyl 4-methyl-5-oxopyrrolidine-1,2-dicarboxylate; 1-(Tert-butyl) 2-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicboxylate; (2S-cis)-1,2-Pyrrolidinedicboxylic Acid 4-Methyl-5-oxo-1-(1,1-diMethylethyl) 2-Methyl Ester; (2S,4S)-1-(1,1-dimethylethyl)-4-methyl-5-oxo-1,2-pyrrolidinedicarboxylic acid 2-methyl ester; (2S-cis)-1,2-Pyrrolidinedicarboxylic Acid 4-Methyl-5-oxo-1-(1,1-dimethylethyl) 2-Methyl Ester; METHYL (2S,4S)-1-(TERT-BUTOXYCBONYL)-4-METHYLPYROGLUTAMATE; Methyl (2S,4S)-1-(tert-butoxycarbonyl)-4-methylpyroglutamate; 1,2-Pyrrolidinedicboxylic acid, 4-methyl-5-oxo-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S); methyl (2S,4S)-1-(tert-butyloxycarbonyl)-4-methylpyroglutamate

物化性质

• 分子式: C₁₂H₁₉NO₅
• 分子量: 257.28300
• 精确质量: 257.12600
• PSA: 72.91000
• LogP: 1.26940

合成路线

219844-08-3 ~99% 196394-48-6

文献：The Procter and Gamble Company Patent: US2007/232804 A1, 2007 ; Location in patent: Page/Page column 4; 5 ;

219844-08-3 ~% 196394-49-7 196394-48-6

文献：US2007/232650 A1, ; Page/Page column 5 ;

108963-96-8 74-88-4 ~% 196394-49-7 196394-48-6

文献：WO2012/148775 A1, ; Page/Page column 85 ; WO 2012/148775 A1

4931-66-2 ~% 196394-48-6

文献：Tetrahedron Letters, , vol. 44, # 15 p. 3203 - 3205

108963-96-8 ~% 196394-48-6

文献：Synthesis, , # 8 p. 863 - 865

98-79-3 ~% 196394-48-6

文献：Synthesis, , # 8 p. 863 - 865

108963-96-8 74-88-4 ~% 158392-74-6 196394-49-7 详细

文献：Tetrahedron Letters, , vol. 44, # 15 p. 3203 - 3205

4931-66-2 ~% 196394-49-7 196394-48-6

文献：WO2012/148775 A1, ; WO 2012/148775 A1

24424-99-5 ~% 196394-49-7 196394-48-6

文献：WO2012/148775 A1, ; WO 2012/148775 A1