633335-81-6

• 常用中文名：1-(5-溴-6-氟-1H-吲唑-1-基)乙酮
• 常用英文名：Ethanone, 1-(5-bromo-6-fluoro-1H-indazol-1-yl)-
• CAS号：633335-81-6
• 分子式：C₉H₆BrFN₂O
• 分子量：257.05900
• 发布时间：2018-12-27 17:41:33
• 更新时间：2024-01-08 19:21:47

名称

• 中文名: 1-(5-溴-6-氟-1H-吲唑-1-基)乙酮
• 英文名: 1-(5-bromo-6-fluoroindazol-1-yl)ethanone
• 英文别名: 1H-Indazole,1-acetyl-5-bromo-6-fluoro; 1-ACETYL-5-BROMO-6-FLUOROINDAZOLE; 1-(5-Bromo-6-fluoro-indazol-1-yl)ethanone; 1-acetyl-5-bromo-6-fluoro-1H-indazole; 1-(5-bromo-6-fluoro-1H-indazol-1-yl)ethanone

物化性质

• 分子式: C₉H₆BrFN₂O
• 分子量: 257.05900
• 精确质量: 255.96500
• PSA: 34.89000
• LogP: 2.59800
• 储存条件: 2-8°C，密封，干燥

合成路线

633335-80-5 ~56% 633335-81-6

文献：AMGEN, INC. Patent: WO2006/44860 A2, 2006 ; Location in patent: Page/Page column 37-38 ; WO 2006/044860 A2

52723-82-7 108-24-7 ~% 633335-81-6

文献：GLAXO GROUP LIMITED; BAILEY, James; KING, Nigel Paul; LIN, Xichen; REN, Feng; TAN, Kheng-Chuan; MAK, Sing Yeung Patent: WO2011/72488 A1, 2011 ; Location in patent: Page/Page column 17; 38-39 ; WO 2011/072488 A1

52723-82-7 540-80-7 108-24-7 ~% 633335-81-6

文献：GLAXO WELLCOME HOUSE Patent: US2012/283297 A1, 2012 ; Location in patent: Page/Page column 22 ;

633335-80-5 108-24-7 ~% 633335-81-6

文献：SCHERING CORPORATION Patent: WO2009/152200 A1, 2009 ; Location in patent: Page/Page column 102 ;

366-49-4 ~% 633335-81-6

文献：Venkatraman, Srikanth; Velazquez, Francisco; Gavalas, Stephen; Wu, Wanli; Chen, Kevin X.; Nair, Anilkumar G.; Bennett, Frank; Huang, Yuhua; Pinto, Patrick; Jiang, Yueheng; Selyutin, Oleg; Vibulbhan, Bancha; Zeng, Qingbei; Lesburg, Charles; Duca, Jose; Heimark, Larry; Huang, Hsueh-Cheng; Agrawal, Sony; Jiang, Chuan-Kui; Ferrari, Eric; Li, Cheng; Kozlowski, Joseph; Rosenblum, Stuart; Shih, Neng-Yang; George Njoroge Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 447 - 458

367-29-3 ~% 633335-81-6

文献：Venkatraman, Srikanth; Velazquez, Francisco; Gavalas, Stephen; Wu, Wanli; Chen, Kevin X.; Nair, Anilkumar G.; Bennett, Frank; Huang, Yuhua; Pinto, Patrick; Jiang, Yueheng; Selyutin, Oleg; Vibulbhan, Bancha; Zeng, Qingbei; Lesburg, Charles; Duca, Jose; Heimark, Larry; Huang, Hsueh-Cheng; Agrawal, Sony; Jiang, Chuan-Kui; Ferrari, Eric; Li, Cheng; Kozlowski, Joseph; Rosenblum, Stuart; Shih, Neng-Yang; George Njoroge Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 447 - 458