140171-66-0

• 常用中文名：氨氯地平二甲基酯
• 常用英文名：Amlodipine Dimethyl Ester
• CAS号：140171-66-0
• 分子式：C₁₉H₂₃ClN₂O₅
• 分子量：394.849
• 相关类别： 化学试剂 有机试剂 酯类 甲酯类化合物
• 发布时间：2018-07-14 09:57:06
• 更新时间：2026-08-06 21:31:41
• Amlodipine besilate impurity F, also known as Amlodipine Dimethyl Ester, is a biochemical.

名称

• 中文名: 氨氯地平二甲基酯
• 英文名: dimethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• 中文别名: 苯磺酸氨氯地平杂质F 标准品; 氨氯地平杂质F; 氨氯地平杂质6(氨氯地平杂质F); 氨氯地平杂质; 氨氯地平相关化合物F; 2-[(2-氨基乙氧基)甲基]-4-(2-氯苯基)-6-甲基-1,4-二氢吡啶-3,5-二甲酸二甲酯; 氨氯地平杂质3; 苯磺酸氨氯地平杂质 F; 2-((2-氨基乙氧基)甲基)-4-(2-氯苯基)-6-甲基-1,4-二氢吡啶-3,5-二羧酸二甲酯 (氨氯地平杂质); 阿莫地平杂质F; 苯磺酸氨氯地平F; 2-((2-氨基乙氧基)甲基)-4-(2-氯苯基)-6-甲基-1,4-二氢吡啶-3,5-二羧酸二甲酯; 氨氯地平杂质F苯磺酸盐
• 英文别名: Dimethyl (4RS)-2-[(2-Aminoethoxy)me; Dimethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicboxylate (Amlodipine Impurity); Amlodipine Impurity F Amlodipine Dimethyl Ester; 2-[(2-AMinoethoxy)Methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-Methyl-3,5-pyridinedicboxylic Acid 3,5-diMethyl Ester; diMethyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicboxylate; 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicboxylic acid dimethyl ester; Dimethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicbo; imethyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicboxylate; AMlodipine IMpurity F; Amlodipine Related Compound F; 3,5-Pyridinedicboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3,5-dimethyl ester; Dimethyl (4RS)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicbo; Amlodipine-6; Amlodipine RC F; Dimethyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate; Amlodipine Imp F; 3,5-Dimethyl-4-(2-chlorophenyl)-6-methyl-2-[(2-aminoethoxy)methyl]-1,4-dihydro-3,5-pyridinedicboxy; 3-Methyl 5-Methyl 4-(2-Chlorophenyl)-6-Methyl-2-[[2- [(2-aMinoethoxy)Methyl]-1,4-dihydropyridine-3,5-dicboxylat; Ethyl Methyl (4RS)-2,6-Bis[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicbo; Amlodipine Impurity 6（Amlodipine Impurity F）; Amlodipine Impurity 6; Amlodipine Besilate Impurity F; dimethylamlodipine; Amlodipine impurity 6/Amlodipine Impurity F/Amlodipine Dimethyl Ester/Dimethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicboxylate; Amlodipine impurities1738; UNII-5TQ5PD1804; Amlodipine Related Compound F (Dimethyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-d; f.dimethyl(4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicboxylate; UNII:5TQ5PD1804; Dimethyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicboxylate; 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1; Ethyl Methyl (4RS)-2,6-Bis[(2-aminoethoxy)-methyl]-4-(2-chlo; Amlodipine Impurity F (Amlodipine Methyl Ester); Amlodipine Impurity F Benzenesulfonate; Amlodipine Impurity FQ: What is Amlodipine Impurity F Q: What is the CAS Number of Amlodipine Impurity F Q: What is the storage condition of Amlodipine Impurity F Q: What e the applications of Amlodipine Impurity F; 5-dicboxylic acid dimethyl ester; AMlodipine IMpurity F (DiMethyl IMpurity); 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, dimethyl ester

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 516.6±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₃ClN₂O₅
• 分子量: 394.849
• 闪点: 266.2±30.1 °C
• 精确质量: 394.129547
• PSA: 99.88000
• LogP: 3.63
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.550

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

140171-50-2 ~81% 140171-66-0

文献：ARTESIAN THERAPEUTICS, INC. Patent: WO2004/33444 A1, 2004 ; Location in patent: Page 30; 31-32 ; WO 2004/033444 A1

156366-27-7 98-11-3 ~% 331258-31-2 140171-66-0 详细

文献：WO2003/101965 A1, ; Page 18; 19; 23-25 ;

105-45-3 ~% 140171-66-0

文献：European Journal of Medicinal Chemistry, , vol. 26, # 9 p. 907 - 913

89-98-5 ~% 140171-66-0

文献：European Journal of Medicinal Chemistry, , vol. 26, # 9 p. 907 - 913

21731-17-9 ~% 140171-66-0

文献：European Journal of Medicinal Chemistry, , vol. 26, # 9 p. 907 - 913

111429-90-4 ~% 140171-66-0

文献：European Journal of Medicinal Chemistry, , vol. 26, # 9 p. 907 - 913

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