24085-03-8

• 常用中文名：4-(2-(苄基(叔丁基)氨基)-1-羟基乙基)-2-(羟甲基)苯酚
• 常用英文名：4-[2-[benzyl(tert-butyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol
• CAS号：24085-03-8
• 分子式：C₂₀H₂₇NO₃
• 分子量：329.43300
• 发布时间：2018-12-19 10:03:10
• 更新时间：2026-07-22 00:16:38

名称

• 中文名: 4-(2-(苄基(叔丁基)氨基)-1-羟基乙基)-2-(羟甲基)苯酚
• 英文名: 4-[2-[benzyl(tert-butyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol
• 中文别名: 沙丁胺醇杂质05; 硫酸沙丁胺醇BP杂质E; 沙丁胺醇杂质E; 沙丁醇胺杂质05; 沙丁胺醇杂质5(沙丁胺醇杂质E); N_苄基沙J胺醇; N-苄基沙丁胺醇; 4-(2-(苄基(叔丁基)氨基)-1-羟乙基)-2-(羟甲基)苯酚 (沙丁胺醇杂质); 硫酸沙丁胺醇杂质E 标准品; 沙丁胺醇杂质05(杂质E); 硫酸沙丁胺醇杂质E; 沙丁胺醇杂质E /BP); 左旋沙丁胺醇杂质E
• 英文别名: 1-(4'-Hydroxy-3'-hydroxymethylphenyl)-2-(benzyl-tert-butylamino)ethanol; Salbutamol Impurity E/N-Benzyl Albuterol/1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylbenzylamino)ethanol; Ccris; Einecs -7; 4-(2-(Benzyl(tert-butyl)amino)-1-hydroxyethyl)-2-(hydroxyMethyl)phenol; 1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(benzyl-tert-butylamino)ethanol alpha-((Benzyl-tert-butylamino)methyl)-m-xylene-4,alpha,alpha-triol; 1-(4-Hydroxy-3-hydrox; Salbutamol Imp. E : (1RS)-2-[benzyl(1,1-dimethylethyl)amino]-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanol; 4-(2-(Benzyl (Tert-Butyl)Amino)-1-Hydroxyethyl)-2-(Hydroxymethyl)Phenol N-Benzyl Salbutamol; α1-[[(1,1-Dimethylethyl)(phenylmethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol; Salbutamol Impurity 5; Salbutamol Sulphate Impurity-E; ALPHA1-{[tert-Butyl-(phenylmethyl)-amino]-methyl}-4-hydroxy-1,3-benzenedime; α-[(benzyl-tert-butylamino)methyl]-m-xylene-4,α,α'-triol; Imp. E :(1RS)-2-[Benzyl(1,1-dimethylethyl)amino]-1-[4-hydroxy-3-(hydroxymethyl)-phenyl]ethanol; einecs 246-013-7; Salbutamol Impurity 5（Salbutamol Impurity E）; 2-[BENZYL(TERT-BUTYL)AMINO]-1-(ALPHA,4-DIHYDROXY-M-TOLYL)ETHANOL; Salbutamol Impurity E; 1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylbenzylamino)ethanol; (1RS)-2-[Benzyl(1,1-dimethylethyl)a; Salbutamol Impurity E (N-Benzyl Albuterol); 4-[2-[Benzyl(tert-butyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol; α-[1,1-Dimethylethyl(phenylmethyl)aminomethyl]-4-hydroxy-1,3-benzenedimethanol; 1,3-Benzenedimethanol, a1-[[(1,1-dimethylethyl)(phenylmethyl)amino]methyl]-4-hydroxy; Salbutamol impurity 5/Salbutamol Impurity E/4-(2-(benzyl(tert-butyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol; α1-Benzyl-tert-butylaMinoMethyl-4-hydroxy-M-xylene-α1,α3-diol; (1RS)-2-[benzyl(1,1-dimethylethyl)amino]-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanol; α1-[(Benzyl-tert-butylaMino)Methyl]-4-hydroxy-M-xylene-α,α'-diol; 4-(2-(Benzyl(tert-butyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol (Salbutamol Impurity); Salbutamol Sulfate Impurity E; Salbutamol Impurity EQ: What is Salbutamol Impurity E Q: What is the CAS Number of Salbutamol Impurity E Q: What is the storage condition of Salbutamol Impurity E Q: What e the applications of Salbutamol Impurity E; N-Benzyl Albuterol; N-benzyl Sha J amine alcohol; Albuterol Impurity E; Salbutamol Imp E; alpha-[(benzyl-tert-butylamino)methyl]-m-xylene-4,alpha,alpha'-triol; 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)(phenylmethyl)amino]methyl]-4-hydroxy

物化性质

• 密度: 1.162g/cm3
• 沸点: 496ºC at 760 mmHg
• 分子式: C₂₀H₂₇NO₃
• 分子量: 329.43300
• 闪点: 249.6ºC
• 精确质量: 329.19900
• PSA: 63.93000
• LogP: 3.21860
• 蒸汽压: 1.17E-10mmHg at 25°C
• 折射率: 1.6

MSDS

Name: 1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylbenzylamino)ethanol Material Safety Data Sheet Synonym: CAS: 24085-03-8 Section 1 - Chemical Product MSDS Name:1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylbenzylamino)ethanol Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 24085-03-8 1-(4-Hydroxy-3-hydroxymethylphenyl)-2- 246-013-7 Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 24085-03-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 114 - 118 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C20H27NO3 Molecular Weight: 329.44 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 24085-03-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylbenzylamino)ethanol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 24085-03-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 24085-03-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 24085-03-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 海关编码: 2922509090

合成路线

64092-10-0 ~% 24085-03-8

文献：Collin; Hartley; Jack; Lunts; Press; Ritchie; Toon Journal of medicinal chemistry, 1970 , vol. 13, # 4 p. 674 - 680

18559-94-9 100-44-7 ~% 24085-03-8

文献：Sharma, Yogesh Kumar; Agarwal, Dau Dayal; Bhure, Sudesh; Mukharjee, Rajendra Nath; Sahu, Pramod Kumar; Bhardwaj, Santosh E-Journal of Chemistry, 2011 , vol. 8, # 4 p. 1720 - 1727

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海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%