330785-81-4

• 常用中文名：阿伐那非中间体
• 常用英文名：4-(3-Chloro-4-Methoxy-benzylaMino) -2-Methylsulfanyl-pyriMidine-5-carboxylic acid ethyl ester
• CAS号：330785-81-4
• 分子式：C₁₆H₁₈ClN₃O₃S
• 分子量：367.850
• 发布时间：2018-07-16 12:09:12
• 更新时间：2026-07-16 15:17:42

名称

• 中文名: 阿伐那非中间体
• 英文名: ethyl 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylate
• 中文别名: 阿伐那非杂质P; 4-(3-氯-4-甲氧基苄氨基) -2-甲硫基嘧啶-5-羧酸乙酯; 2-甲巯基-4-(3-氯-4-甲氧基苄氨基)嘧; 4-[(3-氯-4-甲氧苯基)氨基]-2-(甲硫基)嘧啶-5 -甲酸乙酯; 4-(3-氯-4-甲氧基苯氨基)-5-乙氧基羰基-2-甲基噻嘧啶; 4-(3-氯-4-甲氧基苄氨基)-2-甲巯基嘧啶-5-羧酸乙酯; 4-((3-氯-4-甲氧基苄基)氨基)-2-(甲硫基)嘧啶-5-羧酸乙酯; 2-甲硫基-4-(3-氯-4-甲氧基苄胺) -5-羧酸乙酯嘧啶; 4-(3-氯-4-甲氧基苄胺)-5-甲酸乙酯-2-甲硫基嘧啶; 阿伐那非中间体,4-(3-氯-4-甲氧基苯氨基)-5-乙氧基羰 基-2-甲基噻嘧啶; 4-[[(3-氯-4-甲氧基苯基)甲基]氨基]-2-甲硫基-5-嘧啶羧酸乙酯; 4-[[(3-氯-4-甲氧基苯基)甲基]氨基]-2-甲硫基-5-嘧啶; 氯-4-甲氧基苄胺基-2-甲巯基-5-乙氧羰基嘧啶; 4-(3-氯-4-甲氧基苄氨基)-2-甲巯基-5-乙氧羰基嘧啶; RSYY(利非司特T)-1; AVANAFIL杂质P; 阿伐那非杂质43; 2-甲硫基-4-(3-氯-4-甲氧基苄胺基)嘧啶-5-羧酸乙酯
• 英文别名: Ethyl 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylate; 5-Pyrimidinecboxylicacid, 4-[[(3-chloro-4-methoxyphenyl)me; T6N CNJ BS1 DM1R CG DO1& EVO2; ethyl 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-cboxylate; 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecboxylic acid ethyl ester; 330-4; 4- (3-Chloro-4-methoxyphenylamino) -5-ethoxycbonyl-2-methylthiapyrimidine; "5-Pyrimidinecboxylic acid,4-[[(3-chloro-4-methoxyphenyl) methyl]amino]-2-(methylthio)ethyl este"; RSYY（Lifiteast)-1; ethyl 4-(3-chloro-4-MethoxybenzylaMino)-2-(Methylthio)pyriMidine-5-cboxylate; Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulphanyl)pyrimidine-5-cboxylate, 4-[(3-Chloro-4-methoxybenzyl)amino]-5-(ethoxycbonyl)-2-(methylthio)pyrimidine; Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate; 4-(3-Chloro-4-methoxyphenylamino)-5-ethoxycbonyl-2-methylthiopyrimidine; Avanafil intermediates，5-Pyrimidinecboxylicacid, 4-[[(3- chloro-4- methoxyphenyl)methyl]amino]-2- (methylthio)-, ethyl ester; 4-(3-Chloro-4-Methoxy-benzylaMino)-2-Methylsulfanyl-pyriMidine-5-cboxylic acid ethyl ester; Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-cboxylate; (5-PyriMidinecboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]amino]-2-(Methylthio)-,ethyl ester)###NA; 5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-, ethyl ester; (5-PyriMidinecboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]amino]-2-(Methylthio)-,ethyl ester); Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulphanyl)pyrimidine-5-cboxylate; 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycbonyl-2-MethylthiopyriMidine; Ethyl 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecboxylate; Avanafil Intermediate II; INTERMEDIATE OF AVANAFIL; AvafilImpurity43; Avanafil Intermediate Impurity

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 514.9±45.0 °C at 760 mmHg
• 分子式: C₁₆H₁₈ClN₃O₃S
• 分子量: 367.850
• 闪点: 265.2±28.7 °C
• 精确质量: 367.075745
• PSA: 101.87000
• LogP: 6.05
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.608
• 储存条件: -20°C，避光保存于惰性气体中

安全

• 海关编码: 2933599090

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海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%