156474-21-4

• 常用中文名：(R)-1-((R)-环氧乙烷-2-基)-2-苯基乙基)氨基甲酸叔丁酯
• 常用英文名：(2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane
• CAS号：156474-21-4
• 分子式：C₁₅H₂₁NO₃
• 分子量：263.33200
• 发布时间：2017-01-10 23:30:30
• 更新时间：2026-07-17 12:46:06

名称

• 中文名: (R)-1-((R)-环氧乙烷-2-基)-2-苯基乙基)氨基甲酸叔丁酯
• 英文名: 2-Methyl-2-propanyl {(1R)-1-[(2R)-2-oxiranyl]-2-phenylethyl}carba mate
• 中文别名: 阿扎那韦杂质22; 阿杂那韦或地瑞那韦杂质1; 阿扎那韦杂质47; 阿扎那韦杂质24; (2R,3R)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷
• 英文别名: tert-Butyl 8-quinolyl carbonate; tert-Butyl ((R)-1-((R)-oxiran-2-yl)-2-phenylethyl)cbamate; O-tert-butoxycarbonyl-8-hydroxyquinoline; (R,R)-1-oxiranyl-2-phenylethylcarbamic acid tert-butyl ester; Atazanavir Impurity 47; carbonic acid tert-butyl ester quinolin-8-yl ester; 2-Methyl-2-propanyl {(1R)-1-[(2R)-2-oxiranyl]-2-phenylethyl}cba mate; tert-Butyl-<8>chinolyl-carbonat; [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butyl ester; tert-butyl (quinolin-8-yl)carbonate; tert-butyl [(2R,3R)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate; tert-butyl (R)-(2'-oxo-1'-{[2-(trimethylsilyl)ethoxy]methyl}-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)carbamate; 8-t-Butoxycarbonyloxychinolin; tert-Butyl-chinolyl-(8)-carbonat; tert-butyl (R)-1-((R)-oxiran-2-yl)-2-phenylethylcarbamate; (2R,3R)-3-[(t-Butoxycbonyl)amino]-4-phenyl-1,2-oxybutane; (2R,3R)-1,2-oxy-(Boc amino)-4-phenylbutane; Cbamic acid, N-[(1R)-1-(2R)-2-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester; tert-butyl [(R,R)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate

物化性质

• 分子式: C₁₅H₂₁NO₃
• 分子量: 263.33200
• 精确质量: 263.15200
• PSA: 54.35000
• LogP: 2.72560

合成路线

923601-69-8 ~97% 156474-21-4

文献：GILEAD SCIENCES, INC., Patent: WO2008/13834 A1, 2008 ; Location in patent: Page/Page column 35; 36 ; WO 2008/013834 A1

18942-49-9 ~% 156474-21-4

文献：Bakshi, Pancham; Wolfe, Michael S. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6485 - 6489

673-06-3 ~% 156474-21-4

文献：Babu, Kilaru Ravendra; Rao, Valasani Koteswara; Sudhakar, Yellapu; Raju, Chamarthi Naga Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 6 p. 849 - 854

21685-51-8 ~% 156474-21-4

文献：Babu, Kilaru Ravendra; Rao, Valasani Koteswara; Sudhakar, Yellapu; Raju, Chamarthi Naga Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 6 p. 849 - 854

19901-50-9 ~% 156474-21-4

文献：Babu, Kilaru Ravendra; Rao, Valasani Koteswara; Sudhakar, Yellapu; Raju, Chamarthi Naga Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 6 p. 849 - 854

150935-37-8 ~% 156474-21-4

文献：Babu, Kilaru Ravendra; Rao, Valasani Koteswara; Sudhakar, Yellapu; Raju, Chamarthi Naga Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 6 p. 849 - 854

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