101018-80-8

• 常用中文名：(1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-BUTYL-2-(1-PIPERIDINYLM ETHYL)-
• 常用英文名：(1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-BUTYL-2-(1-PIPERIDINYLM ETHYL)-
• CAS号：101018-80-8
• 分子式：C₂₀H₂₅N₃OS
• 分子量：355.49700
• 发布时间：2017-03-26 11:44:21
• 更新时间：2024-04-03 12:57:35

名称

• 英文名: 1-butyl-2-(piperidin-1-ylmethyl)thiochromeno[3,4-d]imidazol-4-one

物化性质

• 密度: 1.28g/cm3
• 沸点: 547.7ºC at 760mmHg
• 分子式: C₂₀H₂₅N₃OS
• 分子量: 355.49700
• 闪点: 285.1ºC
• 精确质量: 355.17200
• PSA: 66.37000
• LogP: 4.33510
• 蒸汽压: 4.74E-12mmHg at 25°C
• 折射率: 1.672

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DL9829670 CHEMICAL NAME : (1)Benzothiopyrano(3,4-d)imidazol-4(1H)-one, 1-butyl-2-(1-piperidinylmethyl)- CAS REGISTRY NUMBER : 101018-80-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H25-N3-O-S MOLECULAR WEIGHT : 355.54 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,599,1985

合成路线

110-89-4 101018-92-2 ~94% 101018-80-8

文献：Savel'ev, V. L.; Pryanishnikova, N. T.; Afanas'eva, T. G.; Chernyakova, I. V.; Troitskaya, V. S.; Zagorevskii, V. A. Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 9 p. 599 - 601 Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 9 p. 1057 - 1060

59647-34-6 ~% 101018-80-8

文献：Savel'ev, V. L.; Pryanishnikova, N. T.; Afanas'eva, T. G.; Chernyakova, I. V.; Troitskaya, V. S.; Zagorevskii, V. A. Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 9 p. 599 - 601 Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 9 p. 1057 - 1060