76980-28-4

• 常用中文名：(2S)-2-[(2-methoxypyridine-3-carbonyl)amino]pentanedioic acid
• 常用英文名：(2S)-2-[(2-methoxypyridine-3-carbonyl)amino]pentanedioic acid
• CAS号：76980-28-4
• 分子式：C₁₂H₁₄N₂O₆
• 分子量：282.24900
• 发布时间：2017-01-18 10:46:19
• 更新时间：2024-01-10 18:28:40

名称

• 英文名: (2S)-2-[(2-methoxypyridine-3-carbonyl)amino]pentanedioic acid
• 英文别名: Glutamic acid,N-(2-methoxynicotinoyl); N-2-Methoxynicotinoylglutamic acid

物化性质

• 密度: 1.392g/cm3
• 沸点: 559.6ºC at 760 mmHg
• 分子式: C₁₂H₁₄N₂O₆
• 分子量: 282.24900
• 闪点: 292.2ºC
• 精确质量: 282.08500
• PSA: 125.82000
• LogP: 0.52890
• 折射率: 1.567

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MA1350000 CHEMICAL NAME : Glutamic acid, N-(2-methoxynicotinoyl)- CAS REGISTRY NUMBER : 76980-28-4 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H14-N2-O6 MOLECULAR WEIGHT : 282.28 WISWESSER LINE NOTATION : T6NJ BO1 CVMYVQ2VQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,612,1980

合成路线

16498-81-0 ~% 76980-28-4

文献：Zhmurenko, L. A.; Borisenko, S. A.; Glozman, O. M.; Ostrovskaya, R. U.; Burov, Yu. V.; Zagorevskii, V. A. Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 9 p. 612 - 617 Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 9 p. 49 - 55

56-86-0 76988-05-1 ~% 76980-28-4

文献：Zhmurenko, L. A.; Borisenko, S. A.; Glozman, O. M.; Ostrovskaya, R. U.; Burov, Yu. V.; Zagorevskii, V. A. Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 9 p. 612 - 617 Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 9 p. 49 - 55