144702-26-1

• 常用中文名：4'-[[1,4'-二甲基-2'-丙基(2,6'-联-1H-苯并咪唑)-1'-甲基]-[1,1'-联苯基]-2-羧酸叔丁酯
• 常用英文名：4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester
• CAS号：144702-26-1
• 分子式：C₃₇H₃₈N₄O₂
• 分子量：570.72300
• 发布时间：2018-12-01 16:03:42
• 更新时间：2026-07-10 09:17:59

名称

• 中文名: 4'-[[1,4'-二甲基-2'-丙基(2,6'-联-1H-苯并咪唑)-1'-甲基]-[1,1'-联苯基]-2-羧酸叔丁酯
• 英文名: Telmisartan tert-Butyl Ester
• 中文别名: 替米沙坦叔丁酯; 替米沙坦杂质3(替米沙坦杂质C); 替米沙坦欧洲药典杂质 C; 4'-[2'-正丙基-1,4'-二甲基-(2,6'-二苯并咪; 叔丁基 4'-((1,7'-二甲基-2'-丙基-1H,3'H-[2,5'-联苯并[D]咪唑]-3'-基)甲基)-[1, 1'-联苯]-2-羧酸盐 (替米沙坦杂质); 替米沙坦杂质B; 替米沙坦杂质; 1,4'-二甲基-(2,6'-二苯并咪; 替米沙坦杂质C; 沙坦类中间体
• 英文别名: 1,1-Dimethylethyl 4'-[[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]meth; TelMistan tert-Butyl Ester; Telmistan Impurity CQ: What is Telmistan Impurity C Q: What is the CAS Number of Telmistan Impurity C Q: What is the storage condition of Telmistan Impurity C Q: What e the applications of Telmistan Impurity C; 1,1-Dimethylethyl 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-cboxylate; 4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-cboxylic acid 1,1-dimethylethyl ester; tert-butyl 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoate; Telmistan Impurity C（）; tert-butyl 4,-((1,7,-dimethyl-2,-propyl-1H,3,H-[2,5,-bibenzo[d]imidazol]-3,-yl)methyl)-[1,1,-biphenyl]-2-cboxylate; Telmistan Impurity C (Telmistan t-Butyl Ester); Telmistan - Impurity C (Freebase); Telmistan tert-Butyl Ester: tert-Butyl 4′-[(1,7′-dimethyl-2′-propyl-1H,3′,5′-bibenzo[d]imidazol-3′-yl)methyl]biphenyl -2-cboxylatee; 1,4'-DiMethyl-2'-propyl(2,6'-bi-1H-benziMidazol)-1'-yl -Methyl -1,1'-biphenyl-2-cboxylic acid 1,1-diMethylethyl ester; 2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl] methyl}phenyl)benzoic acid t-butyl ester; 4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1; Telmistan t-Butyl Ester; Telmisatran impurity C; Telmistan impurities1040; tert-Butyl 4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-cboxylate (Telmistan Impurity); 4'-[2'-n-Propyl-1,4'-dimethyl-(2,6'-dibenzimidazolyl)-1'-yl]methylene(1,1'-biphenyl)-2-cboxylatemethylester; 4′-[[1,4′-Dimethyl-2′-propyl(2,6′-bi-1H-benzimidazol)-1′-yl]-methyl]-1,1′-biphenyl-2-cboxylic acid 1,1-dimethylethyl ester; Telmistan Impurity 3(Telmistan Impurity C); 4'-1,4'-DIMETHYL-2'-PROPYL(2,6'-BI-1H-BENZIMIDAZOL)-1'-YL-METHYL-1,1'-BIPHENYL-2-CBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER; 2-[4-[[4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]phenyl]benzoic acid tert-butyl ester; [1,1'-Biphenyl]-2-cboxylic acid, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4'-[[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl]biphenyl-2-cboxylate (Telmistan tert-Butyl Ester); TelMistan IMpurity C; Telmisartan Impurity 3; 4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]; [1,1'-Biphenyl]-2-cboxylic acid, 4'-[(1,4'-diMethyl-2'- propyl[2,6'-bi-1H-benziMidazol]-1'-yl)Methyl]-,1,1- diMethylethyl ester

物化性质

• 密度: 1.16
• 沸点: 780.446ºC at 760 mmHg
• 分子式: C₃₇H₃₈N₄O₂
• 分子量: 570.72300
• 闪点: 425.798ºC
• 精确质量: 570.29900
• PSA: 61.94000
• LogP: 8.52150
• 外观性状: 粉末
• 储存条件: 室温

合成路线

1190092-31-9 612-28-2 ~62% 144702-26-1

文献：ZAKLADY FARMACEUTYCZNE POLPHARMA SA Patent: WO2009/123483 A1, 2009 ; Location in patent: Page/Page column 18-19 ;

114772-40-6 152628-02-9 ~72% 144702-26-1

文献：Kumar, A. Sanjeev; Ghosh, Samir; Mehta Journal of Chemical Research, 2010 , # 2 p. 95 - 97

18595-14-7 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

301533-59-5 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

152628-01-8 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

152628-00-7 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

675882-71-0 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

25148-68-9 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051

152628-03-0 ~% 144702-26-1

文献：Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051