63980-43-8

63980-43-8结构式

常用中文名：1-苄基-4-(4-吡啶) 哌嗪
常用英文名：1-Benzyl-4-(4-pyridinyl) piperazine
CAS号：63980-43-8
分子式：C₁₆H₁₉N₃
分子量：253.34200
发布时间：2019-02-17 19:29:12
更新时间：2024-01-13 15:19:41

中文名	1-苄基-4-(4-吡啶) 哌嗪
英文名	1-benzyl-4-pyridin-4-ylpiperazine
英文别名	1-benzyl-4-pyridin-4-yl-piperazine

密度	1.129g/cm3
沸点	394.8ºC at 760mmHg
分子式	C₁₆H₁₉N₃
分子量	253.34200
闪点	192.6ºC
精确质量	253.15800
PSA	19.37000
LogP	2.40670
折射率	1.605

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TK8575000

CHEMICAL NAME :: Piperazine, 1-benzyl-4-(4-pyridyl)-

CAS REGISTRY NUMBER :: 63980-43-8

BEILSTEIN REFERENCE NO. :: 0538975

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H19-N3

MOLECULAR WEIGHT :: 253.38

WISWESSER LINE NOTATION :: T6N DNTJ A1R& D- DT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,541,1963

2759-28-6

19524-06-2

~55%

63980-43-8

文献：Schering Corporation Patent: US2004/106794 A1, 2004 ; Location in patent: Page 160-161 ; US 20040106794 A1

2759-28-6

7379-35-3

~88%

63980-43-8

文献：Kotsuki, Hiyoshizo; Sakai, Hiromitsu; Shinohara, Toshio Synlett, 2000 , # 1 p. 116 - 118

2759-28-6

1120-87-2

~10%

63980-43-8

文献：Manetti, Dina; Bartolini, Alessandro; Borea, Pier Andrea; Bellucci, Cristina; Dei, Silvia; Ghelardini, Carla; Gualtieri, Fulvio; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Varani, Katia Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 3 p. 457 - 465

626-61-9

2759-28-6

~95%

63980-43-8

文献：Bergbreiter, David E.; Osburn, Philip L.; Li, Chunmei Organic Letters, 2002 , vol. 4, # 5 p. 737 - 740

59325-12-1

63980-43-8

文献：Bergbreiter, David E.; Osburn, Philip L.; Li, Chunmei Organic Letters, 2002 , vol. 4, # 5 p. 737 - 740

100-44-7

63980-43-8

文献：Bergbreiter, David E.; Osburn, Philip L.; Li, Chunmei Organic Letters, 2002 , vol. 4, # 5 p. 737 - 740

上游产品 7
2759-28-6 19524-06-2 7379-35-3 1120-87-2
626-61-9 59325-12-1 100-44-7
下游产品 1
1008-91-9

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