14529-12-5

• 常用中文名：N-甲基-5-氯靛红酸酐
• 常用英文名：6-CHLORO-1-METHYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE
• CAS号：14529-12-5
• 分子式：C₉H₆ClNO₃
• 分子量：211.60200
• 发布时间：2018-03-13 08:00:00
• 更新时间：2024-01-04 14:15:30

名称

• 中文名: 5-氯-N-甲基靛红酸酐
• 英文名: 6-chloro-1-methyl-3,1-benzoxazine-2,4-dione
• 中文别名: N-甲基-5-氯靛红酸酐; 6-氯-1-甲基-2H-3,1-苯并恶嗪-2,4(1H)-二酮
• 英文别名: 5-CHLORO-N-METHYLISATOIC ANHYDRIDE; F1943-0050; N-methyl-5-chloroisatoic anhydride; EINECS 238-551-6; N-methyl-6-chloroisatoic anhydride; 6-Chloro-N-methyl IA

物化性质

• 密度: 1.476 g/cm3
• 沸点: 346.9ºC at 760 mmHg
• 熔点: 113℃
• 分子式: C₉H₆ClNO₃
• 分子量: 211.60200
• 闪点: 163.6ºC
• 精确质量: 211.00400
• PSA: 52.21000
• LogP: 1.14510
• 蒸汽压: 5.57E-05mmHg at 25°C
• 折射率: 1.597
• 储存条件: 2-8℃

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DM3120000 CHEMICAL NAME : 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-methyl- CAS REGISTRY NUMBER : 14529-12-5 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C9-H6-Cl-N-O3 MOLECULAR WEIGHT : 211.61 WISWESSER LINE NOTATION : T66 BNVOVJ B1 HG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 17400 mg/kg SEX/DURATION : male 8 day(s) pre-mating female 21 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,7,1966

合成路线

201230-82-2 932-96-7 ~78% 14529-12-5

文献：Guan, Zheng-Hui; Chen, Ming; Ren, Zhi-Hui Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17490 - 17493,4

4743-17-3 74-83-9 ~72% 14529-12-5

文献：Clark, Rachel L.; Clements, Carol J.; Barrett, Michael P.; MacKay, Simon P.; Rathnam, Rajendra P.; Owusu-Dapaah, George; Spencer, John; Huggan, Judith K. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6019 - 6033

4743-17-3 74-88-4 ~91% 14529-12-5

文献：ALFA WASSERMANN S.p.A. Patent: EP620210 A1, 1994 ;

60434-13-1 ~% 14529-12-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 17 p. 2427 - 2430

65798-06-3 ~% 14529-12-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 17 p. 2427 - 2430

17630-76-1 ~% 14529-12-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 17 p. 2427 - 2430

106-47-8 ~% 14529-12-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 17 p. 2427 - 2430

4743-17-3 ~% 14529-12-5

文献：Journal of Medicinal Chemistry, , vol. 34, # 4 p. 1492 - 1503

541-41-3 77-78-1 635-21-2 ~% 14529-12-5

文献：Journal of the Indian Chemical Society, , vol. 56, # 7 p. 708 - 711

上下游产品

上游产品  10
201230-82-2 932-96-7 4743-17-3 74-83-9
74-88-4 60434-13-1 65798-06-3 17630-76-1
106-47-8 541-41-3
下游产品  6
77336-50-6 33280-14-7 72952-53-5 909911-74-6
56967-27-2 5973-28-4