2477-73-8

• 常用中文名：6Α-氯-17-乙酰氧基黄体酮
• 常用英文名：Progesterone, 6.α.-chloro-17-hydroxy-, acetate
• CAS号：2477-73-8
• 分子式：C₂₃H₃₁ClO₄
• 分子量：406.94300
• 发布时间：2017-03-14 03:03:50
• 更新时间：2026-07-15 19:21:11

名称

• 中文名: 6Α-氯-17-乙酰氧基黄体酮
• 英文名: Progesterone, 6.α.-chloro-17-hydroxy-, acetate
• 中文别名: 醋酸氯马酮杂质1; 醋酸氯马酮杂质A; 醋酸氯地孕酮杂质A; 醋酸氯地孕酮杂质1; 黄体酮杂质17; 孕酮杂质17; 醋酸氯地孕酮(6Α-氯-17Α-羟基黄体酮醋酸酯)
• 英文别名: Chlormadinone Acetate Imp A; [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate; [(6S,8R,9S,10R,13S,14S,17R)-6-chloro-17-ethanoyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ethanoate; (6α)-17-(Acetyloxy)-6-chloropregn-4-ene-3,20-dione; Progesterone Impurity 17; 17-Acetoxy-9a-chloropregan-4-ene-3,20-dione; Chlormadinone Acetate Impurity A; 6alpha-Chloro-17-acetoxyprogesterone; acetic acid [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester; 6α-Chloro-17-acetoxy Progesterone (Contain ~ 6-β isoMer); 6α-Chloro-17-hydroxyprogesterone Acetate; Chlormadinone acetate Impurity 1; Chlormadinone Acetate Impurity Ⅰ:6α-Chloro-17-acetoxy Progesterone; 6α-Chloro-17-acetoxy Progesterone (Contain up to 6-β isoMer); 6a-chloro-17-acetoxyprogesterone; 6α-Chloro-17-acetoxy Progesterone

物化性质

• 密度: 1.21g/cm3
• 沸点: 519.3ºC at 760 mmHg
• 分子式: C₂₃H₃₁ClO₄
• 分子量: 406.94300
• 精确质量: 406.19100
• PSA: 60.44000
• LogP: 4.62650
• 蒸汽压: 6.95E-11mmHg at 25°C
• 折射率: 1.549

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU5010390 CHEMICAL NAME : Pregn-4-ene-3,20-dione, 6-alpha-chloro-17-hydroxy-, acetate CAS REGISTRY NUMBER : 2477-73-8 LAST UPDATED : 198910 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H31-Cl-O4 MOLECULAR WEIGHT : 406.99 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported DOSE : 80 mg/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,57,1965

合成路线

2658-74-4 ~% 2477-73-8

文献：Journal of the American Chemical Society, , vol. 81, p. 3485

16319-93-0 ~% 2477-73-8

文献：Journal of the American Chemical Society, , vol. 81, p. 3485

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