923289-21-8

• 常用中文名：2-(4-异丙基噻唑-2-基)-7-甲氧基-8-甲基喹啉-4-醇
• 常用英文名：2-(4-Isopropyl-1,3-thiazol-2-yl)-7-methoxy-8-methylchinolin-4-ol
• CAS号：923289-21-8
• 分子式：C₁₇H₁₈N₂O₂S
• 分子量：314.402
• 发布时间：2018-12-30 20:45:48
• 更新时间：2024-01-02 17:43:35

名称

• 中文名: 2-(4-异丙基噻唑-2-基)-7-甲氧基-8-甲基喹啉-4-醇
• 英文名: 7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)-1H-quinolin-4-one
• 英文别名: 2-(4-Isopropyl-1,3-thiazol-2-yl)-7-methoxy-8-methyl-4-quinolinol; 2-(4-Isopropyl-1,3-thiazol-2-yl)-7-methoxy-8-methylquinolin-4-ol; 4-Quinolinol, 7-methoxy-8-methyl-2-[4-(1-methylethyl)-2-thiazolyl]-; 2-(4-isopropylthiazol-2-yl)-4-hydroxy-7-methoxy-8-methyl-quinoline; 4-hydroxy-2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinoline; FD7118; 2-(4-Isopropyl-1,3-thiazol-2-yl)-7-methoxy-8-methylchinolin-4-ol; 2-isopropylthiazolyl-7-methoxy-8-methylquinolin-4-ol; 4-hydroxy-2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinoline; 2-(4-Isopropyl-thiazol-2-yl)-7-methoxy-8-methyl-quinolin-4-ol; 8-methyl-2-[4-(1-methylethyl)-1,3-thiazol-2-yl]-7-(methyloxy)-4-quinolinol

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 518.0±60.0 °C at 760 mmHg
• 分子式: C₁₇H₁₈N₂O₂S
• 分子量: 314.402
• 闪点: 267.1±32.9 °C
• 精确质量: 314.108887
• PSA: 83.48000
• LogP: 6.12
• 外观性状: 灰色固体
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.635
• 储存条件: 2-8°C

安全

• 海关编码: 2934100090

合成路线

923289-20-7 ~10% 923289-21-8

文献：Kazmierski, Wieslaw M.; Hamatake, Robert; Duan, Maosheng; Wright, Lois L.; Smith, Gary K.; Jarvest, Richard L.; Ji, Jing-Jing; Cooper, Joel P.; Tallant, Matthew D.; Crosby, Renae M.; Creech, Katrina; Wang, Amy; Li, Xianfeng; Zhang, Suoming; Zhang, Yong-Kang; Liu, Yang; Ding, Charles Z.; Zhou, Yasheen; Plattner, Jacob J.; Baker, Stephen J.; Bu, Wei; Liu, Liang Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3021 - 3026

19500-02-8 ~% 923289-21-8

文献：Journal of Medicinal Chemistry, , vol. 55, # 7 p. 3021 - 3026

801281-88-9 ~% 923289-21-8

文献：Synthesis (Germany), , vol. 46, # 7 art. no. 1831, p. 899 - 908

801281-89-0 ~% 923289-21-8

文献：Synthesis (Germany), , vol. 46, # 7 art. no. 1831, p. 899 - 908

563-80-4 ~% 923289-21-8

文献：Journal of Medicinal Chemistry, , vol. 55, # 7 p. 3021 - 3026

912347-94-5 ~% 923289-21-8

文献：Journal of Medicinal Chemistry, , vol. 55, # 7 p. 3021 - 3026

1108658-73-6 ~% 923289-21-8

文献：Journal of Medicinal Chemistry, , vol. 55, # 7 p. 3021 - 3026

19967-55-6 ~% 923289-21-8

文献：Journal of Medicinal Chemistry, , vol. 55, # 7 p. 3021 - 3026

上下游产品

上游产品  6
923289-20-7 19500-02-8 563-80-4 912347-94-5
1108658-73-6 19967-55-6
下游产品  0

海关

海关编码	2934100090
中文概述	2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%