404-25-1

• 常用中文名：Acetamide, N-(4-chlorophenyl)-2,2,2-trifluoro-
• 常用英文名：Acetamide, N-(4-chlorophenyl)-2,2,2-trifluoro-
• CAS号：404-25-1
• 分子式：C₈H₅ClF₃NO
• 分子量：223.58000
• 发布时间：2017-06-02 17:53:37
• 更新时间：2024-01-06 10:16:06

名称

• 英文名: N-(4-chlorophenyl)-2,2,2-trifluoroacetamide
• 英文别名: p-chloro-N-trifluoroacetylaniline; ACETANILIDE,4'-CHLORO-2,2,2-TRIFLUORO; N-4-chlorophenyltrifluoroacetamide; 4'-Chloro-2,2,2-trifluoroacetanilide

物化性质

• 密度: 1.482g/cm3
• 沸点: 276.4ºC at 760 mmHg
• 分子式: C₈H₅ClF₃NO
• 分子量: 223.58000
• 闪点: 121ºC
• 精确质量: 223.00100
• PSA: 29.10000
• LogP: 2.91380
• 蒸汽压: 0.00481mmHg at 25°C
• 折射率: 1.52

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AE1845200 CHEMICAL NAME : Acetanilide, 4'-chloro-2,2,2-trifluoro- CAS REGISTRY NUMBER : 404-25-1 BEILSTEIN REFERENCE NO. : 2107044 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H5-Cl-F3-N-O MOLECULAR WEIGHT : 223.59 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 669 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 39,403,1984

合成路线

106-47-8 407-25-0 ~86% 404-25-1

文献：Johnstrom; Stone-Elander Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 2 p. 135 - 145

106-47-8 76-05-1 ~93% 404-25-1

文献：Han, Ki-Jong; Kim, Misoo Letters in Organic Chemistry, 2011 , vol. 8, # 8 p. 559 - 561

2923-18-4 106-47-8 ~88% 404-25-1

文献：Zhou, Qi-Zhong; Chen, Zhen-Chu Synthetic Communications, 2000 , vol. 30, # 17 p. 3189 - 3194

143681-32-7 ~% 404-25-1

文献：Tsabedze, Sinele B.; Kabotso, Daniel E.K.; Pohl, Nicola L.B. Tetrahedron Letters, 2013 , vol. 54, # 51 p. 6983 - 6985

上下游产品

上游产品  5
106-47-8 407-25-0 76-05-1 2923-18-4
143681-32-7
下游产品  3
22774-67-0 22753-82-8 2131-55-7