31173-14-5

• 常用中文名：2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol
• 常用英文名：2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol
• CAS号：31173-14-5
• 分子式：C₁₂H₁₆F₃NO
• 分子量：247.25700
• 发布时间：2017-04-19 17:36:58
• 更新时间：2024-01-10 05:59:05

名称

• 英文名: 2-({1-[3-(Trifluoromethyl)phenyl]-2-propanyl}amino)ethanol
• 英文别名: 1-(3-trifluoromethyl phenyl)-2-(2-hydroxyethyl)-amino propane; 2-({1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl}amino)ethanol; 4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-pyridin-3-ylamine; 1-(3-Amino-4-pyridyl)-4-(m-trifluoromethylphenyl)piperazine; 1-(3-Trifluormethylphenyl)-4-(3-aminopyrid-4-yl)-piperazin; 4-(m-Trifluoromethylphenyl)-1-(3-amino-4-pyridyl)piperazine; N-{2-[1-methyl-2-(3-trifluoromethyl)phenyl]ethyl}aminoethanol

物化性质

• 密度: 1.166g/cm3
• 沸点: 317.2ºC at 760mmHg
• 分子式: C₁₂H₁₆F₃NO
• 分子量: 247.25700
• 闪点: 145.6ºC
• 精确质量: 247.11800
• PSA: 32.26000
• LogP: 2.60920
• 折射率: 1.475

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KL8235000 CHEMICAL NAME : Ethanol, 2-(alpha-methyl-m-trifluoromethylphenethylamino)- CAS REGISTRY NUMBER : 31173-14-5 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H16-F3-N-O MOLECULAR WEIGHT : 247.29 WISWESSER LINE NOTATION : Q2M1Y1&R CXFFF HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 184 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970

合成路线

21906-39-8 141-43-5 ~44% 31173-14-5

文献：Caldirola, P.; Zandberg, P.; Mannhold, R.; Timmerman, H. European Journal of Medicinal Chemistry, 1993 , vol. 28, # 7-8 p. 555 - 568

75-21-8 1886-26-6 ~% 31173-14-5

文献：Science Union et Cie. Patent: FR1517587 , 1968 ; Chem.Abstr., 1969 , vol. 70, # 106229

上下游产品

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21906-39-8 141-43-5 75-21-8 1886-26-6
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