17380-19-7

• 常用中文名：3-acetyl-indole-5-carbonitrile
• 常用英文名：3-acetyl-indole-5-carbonitrile
• CAS号：17380-19-7
• 分子式：C₁₁H₈N₂O
• 分子量：184.19400
• 发布时间：2017-06-09 01:24:27
• 更新时间：2024-01-08 22:24:48

名称

• 英文名: 3-Acetyl-1H-indole-5-carbonitrile
• 英文别名: 5-cyano-3-acetylindole; 3-Acetyl-5-cyan-indol; INDOLE-5-CARBONITRILE,3-ACETYL; 5-Cyano-3-indolylmethyl ketone; 3-acetyl-indole-5-carbonitrile

物化性质

• 密度: 1.28g/cm3
• 沸点: 418ºC at 760 mmHg
• 分子式: C₁₁H₈N₂O
• 分子量: 184.19400
• 闪点: 206.6ºC
• 精确质量: 184.06400
• PSA: 56.65000
• LogP: 2.24218
• 蒸汽压: 3.38E-07mmHg at 25°C
• 折射率: 1.647

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NL5993130 CHEMICAL NAME : Indole-5-carbonitrile, 3-acetyl- CAS REGISTRY NUMBER : 17380-19-7 BEILSTEIN REFERENCE NO. : 0391186 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H8-N2-O MOLECULAR WEIGHT : 184.21 WISWESSER LINE NOTATION : T56 BMJ DV1 GCN HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 32 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12036

合成路线

15861-24-2 75-36-5 ~73% 17380-19-7

文献：Okauchi; Itonaga; Minami; Owa; Kitoh; Yoshino Organic letters, 2000 , vol. 2, # 10 p. 1485 - 1487

15861-24-2 ~% 17380-19-7

文献：Xu, Hui; Bin Yang, Wen; Wang, Qin Chemical Biology and Drug Design, 2011 , vol. 78, # 5 p. 864 - 868

32685-23-7 ~% 17380-19-7

文献：Xu, Hui; Bin Yang, Wen; Wang, Qin Chemical Biology and Drug Design, 2011 , vol. 78, # 5 p. 864 - 868