21299-86-5

• 常用中文名：1-(2-phenoxyphenoxy)-3-(propan-2-ylamino)propan-2-ol,hydrochloride
• 常用英文名：1-(2-phenoxyphenoxy)-3-(propan-2-ylamino)propan-2-ol,hydrochloride
• CAS号：21299-86-5
• 分子式：C₁₈H₂₄ClNO₃
• 分子量：337.84100
• 发布时间：2016-11-14 10:23:55
• 更新时间：2024-01-02 11:13:09

名称

• 英文名: 1-(2-phenoxyphenoxy)-3-(propan-2-ylamino)propan-2-ol,hydrochloride
• 英文别名: Ph-QA 33

物化性质

• 沸点: 453.4ºC at 760 mmHg
• 分子式: C₁₈H₂₄ClNO₃
• 分子量: 337.84100
• 闪点: 228ºC
• 精确质量: 337.14400
• PSA: 50.72000
• LogP: 4.40950
• 蒸汽压: 5.18E-09mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UB7560000 CHEMICAL NAME : 2-Propanol, 1-(isopropylamino)-3-(o-phenoxyphenoxy)-, hydrochloride, (+-)- CAS REGISTRY NUMBER : 21299-86-5 LAST UPDATED : 199509 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C18-H23-N-O3.Cl-H MOLECULAR WEIGHT : 337.88 WISWESSER LINE NOTATION : 1Y1&M1YQ1OR BOR &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 810 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 26,343,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 110 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 27,453,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 36 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 26,343,1968 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : >50 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting Behavioral - food intake (animal) REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 26,343,1968