16545-11-2

• 常用中文名：胍甲环素
• 常用英文名：guamecycline
• CAS号：16545-11-2
• 分子式：C₂₉H₃₈N₈O₈
• 分子量：626.66100
• 相关类别： 原料药 抗生素类药物 四环素类药
• 发布时间：2018-09-16 02:26:27
• 更新时间：2026-08-02 11:52:46

名称

• 中文名: 胍甲环素
• 英文名: guamecycline
• 英文别名: Guameciclina; 2-Naphthacenecboxamide, N-[[4-[amino[(aminoiminomethyl)imino]methyl]-1-piperazinyl]methyl]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS); guamecycline //BP; Guamecyclinum; N-[[4-[[(Aminoiminomethyl)amino](imino)methyl]piperazin-1-yl]methyl]tetracycline

物化性质

• 密度: 1.67g/cm3
• 沸点: 849.9ºC at 760mmHg
• 分子式: C₂₉H₃₈N₈O₈
• 分子量: 626.66100
• 闪点: 467.8ºC
• 精确质量: 626.28100
• PSA: 259.86000
• 折射率: 1.763

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QI7610000 CHEMICAL NAME : 2-Naphthacenecarboxamide, N-((4-(amidinoamidino)-1-piperazinyl)methyl)-4-(dimet hylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahyd roxy-6-methyl-1,11-di oxo- CAS REGISTRY NUMBER : 16545-11-2 LAST UPDATED : 198407 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C29-H38-N8-O8 MOLECULAR WEIGHT : 626.75 WISWESSER LINE NOTATION : L E6 C666 BV FV CU GUTTT&J DQ EQ HQ IN1&1 MQ M1 RQ GVM1- AT6N DNTJ DYUM&MYZUM HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,290,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 160 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,182,1978