36761-83-8

• 常用中文名：dechloroethylcyclophosphamide
• 常用英文名：dechloroethylcyclophosphamide
• CAS号：36761-83-8
• 分子式：C₅H₁₂ClN₂O₂P
• 分子量：198.58800
• 发布时间：2016-02-14 04:11:31
• 更新时间：2024-01-14 13:23:27

名称

• 英文名: N-Dechloroethyl Cyclophosphamide
• 英文别名: dechloroethylcyclophosphamide; Asta-4968; N-(2-chloroethy)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; N-(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; deschloroethylcyclophosphamide; 2-[(2-Chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; 3-Deschloroethylifosfamide; N-Dechloroethylcyclophosphamide; 3-Dechloroethylifosfamide; Monochloroethylcyclophosphamide; Monochloroethyl

物化性质

• 密度: 1.3g/cm3
• 沸点: 272.1ºC at 760mmHg
• 分子式: C₅H₁₂ClN₂O₂P
• 分子量: 198.58800
• 闪点: 118.4ºC
• 精确质量: 198.03200
• PSA: 60.17000
• LogP: 1.65250

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RP5788670 CHEMICAL NAME : 2H-1,3,2-Oxazaphosphorin-2-amine, N-(2-chloroethyl)tetrahydro-, 2-oxide CAS REGISTRY NUMBER : 36761-83-8 LAST UPDATED : 199404 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C5-H12-Cl-N2-O2-P MOLECULAR WEIGHT : 198.61 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Bird - chicken Cells - not otherwise specified DOSE/DURATION : 70 mg/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 268,115,1992

安全

• 海关编码: 2934999090

合成路线

72578-61-1 ~% 36761-83-8

文献：Pankiewicz,K. et al. Journal of the American Chemical Society, 1979 , vol. 101, p. 7712 - 7718

72578-68-8 ~% 36761-83-8

文献：Pankiewicz,K. et al. Journal of the American Chemical Society, 1979 , vol. 101, p. 7712 - 7718

72578-67-7 ~% 36761-83-8

文献：Pankiewicz,K. et al. Journal of the American Chemical Society, 1979 , vol. 101, p. 7712 - 7718

119670-13-2 ~71% 36761-83-8

文献：Misiura, Konrad Pharmazie, 2004 , vol. 59, # 9 p. 668 - 672

870-24-6 156-87-6 ~% 36761-83-8

文献：Takamizawa; Iwata; Matsumoto Chemical and Pharmaceutical Bulletin, 1977 , vol. 25, # 11 p. 2900 - 2909

50-18-0 ~% 36761-83-8

文献：Bohnenstengel; Hofmann; Eichelbaum; Kroemer European Journal of Clinical Pharmacology, 1996 , vol. 51, # 3-4 p. 297 - 301

上下游产品

上游产品  7
72578-61-1 72578-68-8 72578-67-7 119670-13-2
870-24-6 156-87-6 50-18-0
下游产品  5
3778-73-2 72578-71-3 1071-28-9 689-98-5
45633-04-3

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%