73278-98-5

• 常用中文名：N-3-[3-(1-哌啶甲基)-苯氧基]丙
• 常用英文名：N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]amine
• CAS号：73278-98-5
• 分子式：C₁₅H₂₄N₂O
• 分子量：248.364
• 发布时间：2018-12-24 18:01:41
• 更新时间：2026-07-02 18:49:55
• 【用途一】
  用作药物罗沙替丁中间体

名称

• 中文名: N-3-[3-(1-哌啶甲基)-苯氧基]丙胺
• 英文名: 3-[3-(piperidin-1-ylmethyl)phenoxy]propan-1-amine
• 中文别名: 3-[3-(1-哌啶基甲基)苯氧基]-1-丙胺; 罗沙替丁杂质2; 3-[3-哌啶甲基苯氧基]丙胺; 罗沙替丁杂质9单体; 罗沙替丁醋酸酯杂质03; 罗沙替丁醋酸杂质3; 罗沙替丁醋酸纤维杂质3; 3-(3-(哌啶-1-基甲基)苯氧基)丙-1-胺
• 英文别名: 3-[3-[(1-piperidinyl)-methyl]phenoxy]propylamine; 3-[3-piperidine methyl phenate] propylamine; 3-[3-(Piperidinomethyl)phenoxy]propylamine; 3-[3-(1-Piperidylmethyl)phenoxy]-1-propanamine; N-[3-[3-(1-Piperidinylmethyl)p; 3-(3-(Piperidin-1-ylMethyl)phenoxy)propan-1-aMine; 3-[3-(1-piperidinomethyl)phenoxy]propylamine; 3-[3-(piperidin-1-ylmethyl)phenoxy]propylamine; N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine; N-[3-(3-aminopropoxy)benzyl]piperidine; 3(3-piperidinylmethylphenoxy)propylamine; 3-[3-(Piperidin-1-ylmethyl)phenoxy]propan-1-amine; 3-(3-(piperidin-1-ylmethyl)phenoxy)propan-1-amine; 3-[3-(1-Piperidinylmethyl)phenoxy]-1-propanamine; 3-[m-(1-piperidinylmethyl)phenoxy]propylamine; 3-(m-Piperidinomethylphenoxy)propylamine; *Pacetamol Impurity 28 (3-Nitrophenol); 3-[3-(1-PIPERIDINYLMETHYL)PHENOXY]PROPYLAMINE; MFCD07787282; 3-[3-(l-Piperidinomethyl)phenoxyl]propytamine; N-{3-[3-(1-piperidinomethyl)phenoxy]}propylamine; 3-(3-PIPERIDIN-1-YLMETHYL-PHENOXY)-PROPYLAMINE; 3-[3-(1-PIPERIDINYLMETHYL) PHENOXY] PROPANAMINE; Roxatidine Acetate Impurity 3; [3-(1-PIPERIDINYLMETHYL)PHENOXY]PROPYLAMINE; N-(3-[3-(1-PIPERIDINOMETHYL)PHENOXY])PROPYLAMINE; N-[3-[3-(1-PIPERIDINYLMETHYL)PHENOXY]PROPYL]AMINE; Roxatidine Amine Impurity 1; [3-(1-PIPERIDINYLMETHYL)PHENOXY]PROPYLAMINE(WXG01189); N-[3-[3-aminopropoxy]benzyl]piperidine; Roxatidine Imp.II (Free Base); Roxatidine Impurity 2; 1-Propanamine, 3-[3-(1-piperidinylmethyl)phenoxy]; 3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 375.8±27.0 °C at 760 mmHg
• 熔点: 70-76ºC
• 分子式: C₁₅H₂₄N₂O
• 分子量: 248.364
• 闪点: 181.1±23.7 °C
• 精确质量: 248.188858
• PSA: 38.49000
• LogP: 2.12
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.549
• 储存条件: 2-8°C，干燥

安全

• 海关编码: 2933399090

合成路线

73279-04-6 14753-26-5 6276-54-6 ~85% 73278-98-5

文献：Snow Brand Milk Products Co., Ltd. Patent: US5317026 A1, 1994 ;

73279-04-6 6276-54-6 ~95% 73278-98-5

文献：Tarpanov, Velichko; Vlahov, Radoslav; Penkov, Miho; Krikorian, Dikran; Parushev, Stoyan; Mechkarova, Pepa; Angelova, Nely; Schunack, Walter Synthetic Communications, 1999 , vol. 29, # 1 p. 15 - 20

110-89-4 ~% 73278-98-5

文献：Synthetic Communications, , vol. 29, # 1 p. 15 - 20

100-83-4 ~% 73278-98-5

文献：Synthetic Communications, , vol. 29, # 1 p. 15 - 20

110-89-4 100-83-4 107-13-1 ~% 73278-98-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 10 p. 1717 - 1720

73279-04-6 ~% 73278-98-5

文献：Arzneimittel-Forschung/Drug Research, , vol. 35, # 7 p. 1025 - 1029

76955-74-3 ~% 73278-98-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 15 p. 3886 - 3890

上下游产品

上游产品  7
73279-04-6 14753-26-5 6276-54-6 110-89-4
100-83-4 107-13-1 76955-74-3
下游产品  7
105150-87-6 108441-34-5 93793-83-0 78273-80-0
127966-78-3 120958-90-9 96924-47-9

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%