667-65-2

• 常用中文名：β-Cortol
• 常用英文名：Beta-Cortol
• CAS号：667-65-2
• 分子式：C₂₁H₃₆O₅
• 分子量：368.50800
• 相关类别： 研究领域 其他
• 发布时间：2017-07-10 07:23:36
• 更新时间：2026-08-23 16:39:28
• Beta-Cortol是成人中存在的雄激素代谢物。

名称

• 中文名: β-皮甾五醇
• 英文名: (3R,5R,8S,9S,10S,11S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,11,17-triol
• 中文别名: 5Β-孕聚糖-3Α,11Β,17,20Β,21-戊醇; BETA-皮甾五醇
• 英文别名: |A-Cortol; BETA-CORTOL; B-cortol crystalline; (2S,3S,4R,5R,6R)-6-[(10S,11R,13S,17R)-17-[(1S)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3,4,5,6-tetrahydroxyoxane-2-cboxylic acid; Cortol-20beta; 5β-pregnan-3α, 11β, 17, 20β, 21-pentol; 5BETA-PREGNAN-3ALPHA,11BETA,17ALPHA,20BETA,21-PENTOL; β-Cortol; 5-beta-pregnane-3-alpha,11-beta,17-alpha,20-beta,21-pentaol; Pregnane-3,11,17,20,21-pentol, (3α,5β,11β,20R); 20beta-Cortol; UNII-K5O9P9J39F; 5-BETA-PREGNAN-3-ALPHA, 11-BETA, 17,20-BETA, 21-PENTOL; B-Cortol; b-cortol; 2-Cortol

物化性质

• 密度: 1.252g/cm3
• 沸点: 564.5ºC at 760 mmHg
• 分子式: C₂₁H₃₆O₅
• 分子量: 368.50800
• 闪点: 255ºC
• 精确质量: 368.25600
• PSA: 101.15000
• LogP: 1.44510
• 折射率: 1.586

生物活性

• 描述: Beta-Cortol是成人中存在的雄激素代谢物。
• 相关类别:
  研究领域 >> 其他
• 靶点:

  Human Endogenous Metabolite

• 参考文献:

  [1]. Jung BH, et al. Endogenous urinary steroids in premenopausal women with uterine leiomyomas. Int J Gynaecol Obstet. 2004 Jan;84(1):55-60.

合成路线

83274-68-4 ~% 667-65-2

文献：Hosoda; Yokohama; Nambara Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4023 - 4028

93206-76-9 ~% 667-65-2

文献：Hosoda; Yokohama; Nambara Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4023 - 4028

95826-65-6 ~% 667-65-2

文献：Hosoda; Yokohama; Nambara Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4023 - 4028

95826-66-7 ~% 667-65-2

文献：Hosoda; Yokohama; Nambara Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4023 - 4028

74563-60-3 ~% 667-65-2

文献：Fukushima et al. Journal of Biological Chemistry, 1955 , vol. 212, p. 449,455

95826-67-8 ~% 667-65-2

文献：Hosoda; Yokohama; Nambara Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4023 - 4028

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