517-83-9

• 常用中文名：4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one
• 常用英文名：4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one
• CAS号：517-83-9
• 分子式：C₂₂H₂₂N₄O₂
• 分子量：374.43600
• 发布时间：2016-05-27 15:46:30
• 更新时间：2024-01-10 16:49:35

名称

• 英文名: 4-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,5-dimethyl-2-phenylpyrazol-3-one
• 英文别名: (4,4'-BI-3-PYRAZOLINE)-5,5'-DIONE,1,1'-DIPHENYL-2,2',3,3'-TETRAMETHYL; 2,2',3,3'-Tetramethyl-1,1'-diphenyl(4,4'-bi-3-pyrazoline)-5,5'-dione; Forbisen; S. N. 475; (4,4'-Bi-1H-pyrazole)-3,3'-dione,2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl

物化性质

• 密度: 1.268g/cm3
• 沸点: 438.6ºC at 760 mmHg
• 分子式: C₂₂H₂₂N₄O₂
• 分子量: 374.43600
• 闪点: 166.2ºC
• 精确质量: 374.17400
• PSA: 53.86000
• LogP: 2.94920
• 折射率: 1.645

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DW4000000 CHEMICAL NAME : (4,4'-Bi-3-pyrazoline)-5,5'-dione, 1,1'-diphenyl-2,2',3,3'-tetramethyl- CAS REGISTRY NUMBER : 517-83-9 BEILSTEIN REFERENCE NO. : 0351034 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H22-N4-O2 MOLECULAR WEIGHT : 374.48 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 15 gm/kg/22W-I TOXIC EFFECTS : Behavioral - ataxia Blood - normocytic anemia Related to Chronic Data - death REFERENCE : 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946

合成路线

74-88-4 ~% 517-83-9

文献：Knorr Chemische Berichte, 1884 , vol. 17, p. 2040 Justus Liebigs Annalen der Chemie, 1887 , vol. 238, p. 160,214 Full Text Show Details Knorr Justus Liebigs Annalen der Chemie, 1887 , vol. 238, p. 160,205 Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 1,26, 41

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