18940-57-3

• 常用中文名：1,4-二乙酰基哌嗪
• 常用英文名：Ethanone,1,1'-(1,4-piperazinediyl)bis-
• CAS号：18940-57-3
• 分子式：C₈H₁₄N₂O₂
• 分子量：170.20900
• 发布时间：2018-07-21 19:23:12
• 更新时间：2024-01-09 15:03:31

名称

• 中文名: 1,4-二乙酰基哌嗪
• 英文名: 1-(4-acetylpiperazin-1-yl)ethanone
• 中文别名: 1.4-二乙酰基哌嗪; 1,4-二乙酰基哌嗪
• 英文别名: 1,1'-(Piperazine-1,4-diyl)diethanone; N,N'-diacetyl piperazine; 1,4-Diacetyl-piperazin; Benzylpiperazine-M (piperazine),2AC; 1,4-Diacetylpiperazine; 1,4-diacetyl-1,4-diazacyclohexane; Piperazine,1,4-diacetyl; Piperazine,4-diacetyl

物化性质

• 密度: 1.126g/cm3
• 沸点: 365.2ºC at 760mmHg
• 分子式: C₈H₁₄N₂O₂
• 分子量: 170.20900
• 闪点: 177.6ºC
• 精确质量: 170.10600
• PSA: 40.62000
• 蒸汽压: 1.6E-05mmHg at 25°C
• 折射率: 1.494
• 储存条件: 室温，干燥密封

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL3499000 CHEMICAL NAME : Piperazine, 1,4-diacetyl- CAS REGISTRY NUMBER : 18940-57-3 BEILSTEIN REFERENCE NO. : 0136055 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H14-N2-O2 MOLECULAR WEIGHT : 170.24 WISWESSER LINE NOTATION : T6N DNTJ AV1 DV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,801,1968

安全

• 海关编码: 2933599090

合成路线

2466-76-4 142-64-3 ~0% 13889-98-0 18940-57-3

文献：Verma, Sanjeev K.; Acharya; Kaushik Organic Letters, 2010 , vol. 12, # 19 p. 4232 - 4235

108-24-7 21943-18-0 ~69% 18940-57-3

文献：Dave, Paritosh R.; Kumar, Kaipenchery A.; Duddu, Rajagopal; Axenrod, Theodore; Dai, Rongji; Das, Kajal K.; Guan, Xiao-Pei; Sun, Jianguang; Trivedi, Nirupam J.; Gilardi, Richard D. Journal of Organic Chemistry, 2000 , vol. 65, # 4 p. 1207 - 1209

110-85-0 141-78-6 ~95% 18940-57-3

文献：Zeynizadeh, Behzad; Zahmatkesh, Karam Journal of the Chinese Chemical Society, 2004 , vol. 51, # 4 p. 801 - 805

110-85-0 2466-76-4 142-64-3 ~% 13889-98-0 详细

文献：Verma, Sanjeev K.; Ghorpade, Ramarao; Pratap, Ajay; Kaushik Green Chemistry, 2012 , vol. 14, # 2 p. 326 - 329

110-85-0 64-19-7 ~41% 13889-98-0 18940-57-3

文献：Ferroud, Clotilde; Godart, Marie; Ung, Stephane; Borderies, Helene; Guy, Alain Tetrahedron Letters, 2008 , vol. 49, # 18 p. 3004 - 3008

110-85-0 108-24-7 ~70% 18940-57-3

文献：Paul, Satya; Nanda, Puja; Gupta, Rajive; Loupy, Andre Tetrahedron Letters, 2002 , vol. 43, # 23 p. 4261 - 4265

108-24-7 ~% 18940-57-3

文献：Schmidt; Wichmann Chemische Berichte, 1891 , vol. 24, p. 3245

上下游产品

上游产品  7
110-85-0 108-24-7 2466-76-4 142-64-3
21943-18-0 141-78-6 64-19-7
下游产品  3
6483-50-7 6302-66-5 4164-37-8

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%