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1905-75-5

1905-75-5结构式
1905-75-5结构式

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中文名 4-苯基-1,2,5-噁二唑-3-胺
英文名 5-phenyl-1,3,4-oxadiazol-2-amine,hydrochloride
英文别名 1,3,2,4-Dioxathiazole,5-phenyl-,2-oxide
5-Phenyl-1,3,2,4-Dioxathiazol-2-oxid
密度 1.276g/cm3
沸点 332.3ºC at 760 mmHg
分子式 C8H8ClN3O
分子量 197.62200
闪点 154.7ºC
精确质量 197.03600
PSA 64.94000
LogP 2.70200
蒸汽压 0.000148mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RO0548600
CHEMICAL NAME :
1,3,4-Oxadiazol-2-amine, 5-phenyl-, monohydrochloride
CAS REGISTRY NUMBER :
1905-75-5
LAST UPDATED :
199203
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H7-N3-O.Cl-H
MOLECULAR WEIGHT :
197.64

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
440 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
>400 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
>60 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961