57536-84-2

• 常用中文名：1-(5,6,7,8-四氢萘-1-基)哌嗪
• 常用英文名：5-piperazinyltetralin
• CAS号：57536-84-2
• 分子式：C₁₄H₂₀N₂
• 分子量：216.32200
• 发布时间：2018-12-16 12:06:16
• 更新时间：2024-01-23 10:36:10

名称

• 中文名: 1-(5,6,7,8-四氢萘-1-基)哌嗪
• 英文名: 5-piperazinyltetralin

物化性质

• 密度: 1.057g/cm3
• 沸点: 396.6ºC at 760 mmHg
• 分子式: C₁₄H₂₀N₂
• 分子量: 216.32200
• 闪点: 185.7ºC
• 精确质量: 216.16300
• PSA: 15.27000
• LogP: 2.36880
• 折射率: 1.564

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TM2785700 CHEMICAL NAME : Piperazine, 1-(5,6,7,8-tetrahydro-1-naphthyl)- CAS REGISTRY NUMBER : 57536-84-2 BEILSTEIN REFERENCE NO. : 0518635 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C14-H20-N2 MOLECULAR WEIGHT : 216.36 WISWESSER LINE NOTATION : L66&TJ B- DT6M DNTJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 18 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#08316

合成路线

821-48-7 2217-41-6 ~51% 57536-84-2

文献：Abbott Laboratories Patent: US6346622 B1, 2002 ; Location in patent: Page column 7 ;

2217-41-6 ~% 57536-84-2

文献：Kuipers, Wilma; Wijngaarden, Ineke van; Kruse, Chris G.; Amstel, Marian ter Horst-van; Tulp, Martin Th. M.; IJzerman, Adriaan P. Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1942 - 1954

29809-14-1 ~% 57536-84-2

文献：Kuipers, Wilma; Wijngaarden, Ineke van; Kruse, Chris G.; Amstel, Marian ter Horst-van; Tulp, Martin Th. M.; IJzerman, Adriaan P. Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1942 - 1954

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