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16154-78-2生产厂家

16154-78-2价格

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16154-78-2

16154-78-2结构式
16154-78-2结构式

化源商城直购

中文名 8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐
英文名 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole hydrochloride
中文别名 吡吲哚盐酸盐
吡吲哚杂质
英文别名 Pirlindole hydrochloride salt
1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-A)indole hydrochloride
pyrazidole hydrochloride
1,10-Trimethylene-8-methyltetrahydropyrazino(1,2-A)indole hydrochloride
2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride
Einecs 240-307-9
Pirlindole HCl
Pirlindole hydrochloride
Pirlindole D3 Hydrochloride
1H-Pyrazino(3,2,1-jk)carbazole,2,3,3A,4,5,6-hexahydro-8-methyl-,monohydrochloride
2,3,3A,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1J,K)carbazole hydrochloride
2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]cbazole monohydrochloride
2,3,3A,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1J,K)cbazole hydrochloride
1H-Pyrazino(3,2,1-jk)cbazole, 2,3,3A,4,5,6-hexahydro-8-methyl-, monohydrochloride
Einecs -9
1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino-(1,2-a) indolhydrochloride
Pyrazidole
密度 1.29g/cm3
沸点 422.6ºC at 760mmHg
分子式 C15H19ClN2
分子量 262.77800
闪点 209.4ºC
精确质量 262.12400
PSA 16.96000
LogP 4.06110
蒸汽压 2.39E-07mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ3930000
CHEMICAL NAME :
1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-, monohydrochloride
CAS REGISTRY NUMBER :
16154-78-2
LAST UPDATED :
199706
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C15-H18-N2.Cl-H
MOLECULAR WEIGHT :
262.81
WISWESSER LINE NOTATION :
T C6566 1A P BN NM&&TTJ F1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2060 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),17,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
185 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),17,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 18,94,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
112 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 38,5,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
175 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 37,192,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
67 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - tremor Lungs, Thorax, or Respiration - other changes
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 38,5,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
122 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4258043 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 ug/m3/4H/30D-I
TOXIC EFFECTS :
Endocrine - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),17,1993

海关编码 2933990090
海关编码 2933990090
中文概述 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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