874340-08-6

• 常用中文名：N-(3-酞酰亚胺基-2-(R)-羟基丙基)-3-氟-4-(吗啉基)苯胺
• 常用英文名：N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline
• CAS号：874340-08-6
• 分子式：C₂₁H₂₂FN₃O₄
• 分子量：399.41500
• 发布时间：2017-12-09 08:46:50
• 更新时间：2025-09-27 19:15:31

名称

• 中文名: N-(3-邻苯二甲酰亚胺基-2-(R)-羟丙基)-3-氟-4-(吗啉基)苯胺
• 英文名: 2-[(2R)-3-(3-fluoro-4-morpholin-4-ylanilino)-2-hydroxypropyl]isoindole-1,3-dione
• 中文别名: 利奈唑胺INT1对照品; 利奈唑胺去乙酰胺去羰基邻苯二甲酰亚胺; 利奈唑胺-去乙酰胺-脱羰基邻苯二甲酰亚胺; 利奈唑胺杂质INT1; 利奈唑胺04; 2-[(2R)-3-[[3-氟-4-(4-吗啉基)苯基]氨基]-2-羟丙基]-1H-异吲哚-1,3(2H)-二酮; (R)-2-(3-(3-氟-4-吗啉基苯氨基)-2-羟甲基)邻苯二甲酰胺; 利奈唑胺脱乙酰胺脱羰基邻苯二甲酰亚胺; 利奈唑胺杂质INT1对照品; N-(3-邻苯二甲酰亚胺-2-(R)-羟丙基)-3-氟-4-(吗啉基)苯胺
• 英文别名: N-[3-phthalimido-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholinyl)-aniline; 2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione; Linezolid impurity INT1 reference substance; Linezolid DesacetaMide Descbonyl PhthaliMide; 2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1,3-isoindolinedione; N-(3-PhthaliMido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline; (R)-Linezolid Desacetamide Descbonyl Phthalimide/Linezolid Desacetamide Descbonyl Phthalimide (R)-Isomer/2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione; (R)-Linezolid Desacetamide Descbonyl Phthalimide; N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(4-morpholinyl)aniline; Linezolid Impurity 18; 2-[(2R)-3-[[3-Fluoro-4-(4-Morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione; (R)-2-(3-((3-Fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl)isoindoline-1,3-dione; Linazolid intermediate; Linezolid impurity INT1; Linezolid Desacetamide Descbonyl Phthalimide (R)-Isomer; 1H-Isoindole-1,3(2H)-dione, 2-[(2R)-3-[[3-fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]; Linezolid impurity 32/N-(3-PhthaliMido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

物化性质

• 分子式: C₂₁H₂₂FN₃O₄
• 分子量: 399.41500
• 精确质量: 399.15900
• PSA: 82.11000
• LogP: 1.80720
• 储存条件: 2-8°C

合成路线

868405-66-7 1074-82-4 ~% 874340-08-6

文献：SYMED LABS LIMITED Patent: WO2006/8754 A1, 2006 ; Location in patent: Page/Page column 11 ;

93246-53-8 161596-47-0 ~% 874340-08-6

文献：SYMED LABS LIMITED Patent: WO2006/8754 A1, 2006 ; Location in patent: Page/Page column 11 ;

93246-53-8 ~% 874340-08-6

文献：Reddy, Pingili Krishna; Mukkanti; Rao, Dodda Mohan Asian Journal of Chemistry, 2012 , vol. 24, # 8 p. 3479 - 3482

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