203395-59-9

• 常用中文名：7-(4-溴丁氧基)-2(1H)喹啉酮
• 常用英文名：7-(4-Bromobutoxy)-2(1H)-quinolinone
• CAS号：203395-59-9
• 分子式：C₁₃H₁₄BrNO₂
• 分子量：296.160
• 发布时间：2018-10-17 12:22:47
• 更新时间：2026-07-14 17:30:48

名称

• 中文名: 阿立哌唑溴代杂质
• 英文名: 7-(4-bromobutoxy)-1H-quinolin-2-one
• 中文别名: 溴乙哌唑杂质28; 7-(4-溴丁氧基)-喹啉-2(1H)-酮; 依匹哌唑中间体; 阿立哌唑溴杂质; 阿立哌唑镇静剂杂质
• 英文别名: 7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE (Related Reference); 2(1H)-Quinolinone,7-(4- broMobutoxy); ipiprazole Bromo Impurity/ 7-(4-bromobutoxy)quinolin-2(1H)-one; iprazole impurity 44; 7-(4-Bromobutoxy)-1H-quinolin-2-one; ipiprazole Bromobutoxyquinolinone Analog; 7-(4-bromobutoxy)quinolin-2(1H)-one/ ipiprazole Bromo Impurity; 7-(4-bromobutoxy)quinolin-2(1H)-one; ipiprazole BroMo IMpurity; 7-(4-BroMobutoxy)-2(1H)-quinolinone; 7-(4-Bromobutoxy)quinolin2(1H)-one / Dehydro Impurity; 7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE; Brexpiprazole Impurity 16 7-(4-Bromobutoxy)-quinoline-2(1H)-one

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 475.3±45.0 °C at 760 mmHg
• 分子式: C₁₃H₁₄BrNO₂
• 分子量: 296.160
• 闪点: 241.3±28.7 °C
• 精确质量: 295.020782
• PSA: 42.35000
• LogP: 3.14
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.583
• 储存条件: 室温，干燥密封

合成路线

110-52-1 70500-72-0 ~40% 203395-59-9

文献：THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; JIN, Jian; ROTH, Bryan; FRYE, Stephen Patent: WO2012/3418 A2, 2012 ; Location in patent: Page/Page column 51 ; WO 2012/003418 A2

129722-34-5 ~% 203395-59-9

文献：Chander, T. Poorna; Satyanarayana; Kumar, N. Ramesh; Reddy, P. Pratap; Anjaneyulu Synthetic Communications, 2007 , vol. 37, # 24 p. 4337 - 4341

536-90-3 ~% 203395-59-9

文献：WO2012/3418 A2, ; WO 2012/003418 A2

15116-41-3 ~% 203395-59-9

文献：WO2012/3418 A2, ; WO 2012/003418 A2

上下游产品

上游产品  5
110-52-1 70500-72-0 129722-34-5 536-90-3
15116-41-3
下游产品  1
129722-25-4