509083-46-9

• 常用中文名：4-{(E)-[1-(3,5-Dichlorophenyl)-3-methyl-2,5-dioxo-4-imidazolidiny lidene]methyl}benzonitrile
• 常用英文名：4-{(E)-[1-(3,5-Dichlorophenyl)-3-methyl-2,5-dioxo-4-imidazolidiny lidene]methyl}benzonitrile
• CAS号：509083-46-9
• 分子式：C₁₈H₁₁Cl₂N₃O₂
• 分子量：372.20500
• 发布时间：2016-10-24 08:03:37
• 更新时间：2024-01-09 15:59:24

名称

• 英文名: 4-{(E)-[1-(3,5-Dichlorophenyl)-3-methyl-2,5-dioxo-4-imidazolidiny lidene]methyl}benzonitrile
• 英文别名: BENZO[1,3]DIOXOLE-4-CARBALDEHYDE; BUTTPARK 272-58; 1,3-BENZODIOXOLE-4-CARBALDEHYDE; (E)-4-((1-(3,5-dichlorophenyl)-3-methyl-2,5-dioxoimidazolidin-4-ylidene)methyl)benzonitrile; (E)-4-((2',3'-methylenedioxy)phenyl)but-3-enoic acid; 4-FORMYL-1,3-BENZODIOXOLE; (E)-4-[-(3,5-dichlorophenyl)-3-methyl-2,5-dioxoimidazolidin-4-ylidenemethyl]-benzonitrile

物化性质

• 分子式: C₁₈H₁₁Cl₂N₃O₂
• 分子量: 372.20500
• 精确质量: 371.02300
• PSA: 64.41000
• LogP: 4.30748

合成路线

105-07-7 27387-90-2 ~85% 509083-46-9

文献：BRISTOL-MYERS SQUIBB COMPANY Patent: WO2006/65908 A1, 2006 ; Location in patent: Page/Page column 35; 64 ;

34893-92-0 ~% 509083-46-9

文献：Potin, Dominiques; Launay, Michele; Monatlik, Francoise; Malabre, Patrice; Fabreguettes, Maud; Fouquet, Andre; Maillet, Magali; Nicolai, Eric; Dorgeret, Loic; Chevallier, Francois; Besse, Dominique; Dufort, Monique; Caussade, Francois; Ahmad, Syed Z.; Stetsko, Dawn K.; Skala, Stacey; Davis, Patricia M.; Balimane, Praveen; Patel, Karishma; Yang, Zheng; Marathe, Punit; Postelneck, Jennifer; Townsend, Robert M.; Goldfarb, Valentina; Sheriff, Steven; Einspahr, Howard; Kish, Kevin; Malley, Mary F.; DiMarco, John D.; Gougoutas, Jack Z.; Kadiyala, Pathanjali; Cheney, Daniel L.; Tejwani, Ravindra W.; Murphy, Denette K.; Mcintyre, Kim W.; Yang, Xiaoxia; Chao, Sam; Leith, Leslie; Xiao, Zili; Mathur, Arvind; Chen, Bang-Chi; Wu, Daugh-Rurng; Traeger, Sarah C.; McKinnon, Murray; Barrish, Joel C.; Robl, Jeffrey A.; Iwanowicz, Edwin J.; Suchard, Suzanne J.; Dhar, T. G. Murali Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 6946 - 6949

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