147489-06-3

• 常用中文名：6-[[(1E)-2-环丙基-4-(4-氟苯基)-3-喹啉基]-乙烯基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯
• 常用英文名：(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
• CAS号：147489-06-3
• 分子式：C₃₂H₃₆FNO₄
• 分子量：517.631
• 发布时间：2018-08-21 18:06:34
• 更新时间：2026-06-30 18:37:41

名称

• 中文名: (4R,6S)-6-[[(1E)-2-环丙基-4-(4-氟苯基)-3-喹啉基]乙烯基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯
• 英文名: t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
• 中文别名: (4R,6S)-6-[(1E)-2-[2-环丙基-4-(4-氟苯基)-3-喹啉基]乙烯基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯; 匹伐他汀中间体3R5S异构体; 匹伐他汀缩合物; 6-[[(1E)-2- 环丙基 -4-(4- 氟苯基 )-3- 喹啉基 ]- 乙烯基 ]-2,2- 二甲基 -1,3- 二氧六环 -4- 乙酸叔丁酯; 匹伐他汀缩合叔丁酯; (3R,5S,6E)-7-[2-环丙基-4-(4-氟苯基)-3-喹啉-基]-2,2-二甲基-1,3-二氧六环-6-庚烯酸叔丁酯; 叔丁基2-(((4R,6S)-6-((E)-2-(2-环丙基-4-(4-氟苯基)喹啉-3-基)乙烯基)-2,2-二甲基-1, 3-二噁烷-4-基)乙酸酯(匹伐他汀杂质); 3-二氧六环-6-庚烯酸叔丁酯; 匹伐他汀(双保护叔丁酯); 匹伐他汀钙杂质5; 6-[[(1E)-2-环丙基-4-(4-氟苯基)-3-喹啉基]-乙烯基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯(匹伐他汀中间体); 匹伐他汀乙酰丙酮叔丁基酯; 匹达伐他汀乙交酯叔丁酯; 匹伐他汀钙杂质F; 6-[[(1E)-2-环丙基-4-(4-氟苯基)-3-喹啉基]-乙烯基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯(简称匹伐他汀钙侧链); 匹伐他汀对接物; 匹伐他汀杂质PF-1; 6-[[(1E)-2-环丙基-4-(4-氟苯基)-3-喹啉基]-乙烯基]-2; 匹伐他汀钙中间体PB4; 6E)-7-[2-环丙基-4-(4-氟苯基)-3-喹啉-基]-2; 匹伐他汀异丙基叔丁酯
• 英文别名: (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4; (3R,5S,E)-tert-butyl7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyht-6-enoate; (4R,6S)-6-[[(1E)-2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]vinyl]-2,2-dimethyl-1, 3-Dioxane-4-acetic acid tert-butyl ester; t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-he; t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin; 2-[6-[2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-butyl ester; tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; 5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3; Tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate (Pitavastatin Impurity); 5-isopropylidenedioxy-6-htenoate; T-Butyl (3R; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)3-quinoline-base]-2,2-dimethyl-1,3-dioxane-6-hteneacidtert-butylester; t-Bytyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluoropenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-htenoate; tert-butyl 2-((4R,6S); Pirvastatin isopropyl tert butyl ester; 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)3-quinoline-base]-2; 6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester (4R,6S)- (9CI ACI); Butyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-htenoate; 2-Methyl-2-propanyl [(4R,6S)-6-{(E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]vinyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate; tert-Butyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-htenoate; tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1; 3-dioxane-6-hteneacidtert-butylester; Pivastatin calcium intermediate; 1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)- (9CI, ACI); t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-hte; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2,2-dimethyl-1,3-dioxane-6-htenoic acid tert-butyl ester; t-Butyl-(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-htenoate; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-2,2-Dimethyl-1,3-dioxane-6- htenoic acid,1,1-dimethylethyl ester; quinolin-3-yl]-3,5-isopropylidenedioxy-6-htenoate; Pitavastatin Calcium Impurity F; 7-[2-cyclopropyl-4-(4-fluorophenyl); t-Butyl (3R,5S); pitavastatin intermediate 3R5S isomer; (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]vinyl]-2,2-dimethyl-1,3-dioxane-4-acetatetert-butylester; 1,3-Dioxane-4-acetic acid,6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-,1,1-dimethylethyl ester,(4R,6S); (4R, 6S) -6- [[(1E) -2-cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] ethenyl] -2,2-dimethyl-1,3-dioxolane-4-acetic acid tert butyl ester

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 604.6±55.0 °C at 760 mmHg
• 分子式: C₃₂H₃₆FNO₄
• 分子量: 517.631
• 闪点: 319.4±31.5 °C
• 精确质量: 517.262817
• PSA: 57.65000
• LogP: 7.05
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.604
• 储存条件: 2-8℃，密闭，干燥

安全

• 海关编码: 2934999090

合成路线

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%