4781-76-4

• 常用中文名：3,4-二氢吡喃甲胺
• 常用英文名：(3,4-DIHYDRO-2H-PYRAN-2-YL)-METHYLAMINE
• CAS号：4781-76-4
• 分子式：C₆H₁₁NO
• 分子量：113.15800
• 发布时间：2018-03-20 08:00:00
• 更新时间：2024-01-04 18:31:09

名称

• 中文名: 3,4-二氢吡喃甲胺
• 英文名: (3,4-dihydro-2h-pyran-2-yl)-methylamine
• 中文别名: 3,4-二氢-2H-吡喃-2-甲胺
• 英文别名: 3,4-Dihydro-2H-pyran-2-methylamine; 3,4-dihydro-2-aminomethyl-2h-pyra; 4H-Pyran,2-aminomethyl-2,3-dihydro; 2-Aminomethyl-2,3-dihydro-4H-pyran; 2H-Pyran,3,4-dihydro-2-aminomethyl; C-(3,4-dihydro-2H-pyran-2-yl)-methylamine; 2-aminomethyl-3,4-dihydro-2H-pyran; 3,4-dihydro-2H-pyran-2-methanamine

物化性质

• 密度: 0.996 g/cm3
• 沸点: 184.1ºC at 760 mmHg
• 分子式: C₆H₁₁NO
• 分子量: 113.15800
• 闪点: 70.5ºC
• 精确质量: 113.08400
• PSA: 35.25000
• LogP: 1.33810
• 折射率: 1.474
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UP7750000 CHEMICAL NAME : 2H-Pyran, 3,4-dihydro-2-aminomethyl- CAS REGISTRY NUMBER : 4781-76-4 BEILSTEIN REFERENCE NO. : 1362797 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C6-H11-N-O MOLECULAR WEIGHT : 113.18 WISWESSER LINE NOTATION : T6O BUTJ F1Z HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 180 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 ppm/6H/8D-I TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death REFERENCE : BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 27,1,1970

合成路线

100-73-2 ~73% 4781-76-4

文献：MERCK PATENT GMBH Patent: WO2009/77052 A2, 2009 ; Location in patent: Page/Page column 28 ;

49831-28-9 ~% 4781-76-4

文献：Krstenansky; Del Rosario-Chow; Currie Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 707 - 711

159691-03-9 ~% 4781-76-4

文献：Jahangiri, Guiti K.; Reymond, Jean-Louis Journal of the American Chemical Society, 1994 , vol. 116, # 25 p. 11264 - 11274

3749-36-8 ~% 4781-76-4

文献：Jahangiri, Guiti K.; Reymond, Jean-Louis Journal of the American Chemical Society, 1994 , vol. 116, # 25 p. 11264 - 11274

3540-36-1 ~% 4781-76-4

文献：Jahangiri, Guiti K.; Reymond, Jean-Louis Journal of the American Chemical Society, 1994 , vol. 116, # 25 p. 11264 - 11274

83568-11-0 ~% 4781-76-4

文献：Krstenansky; Del Rosario-Chow; Currie Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 707 - 711

16698-52-5 ~% 4781-76-4

文献：Krstenansky; Del Rosario-Chow; Currie Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 707 - 711

上下游产品

上游产品  7
100-73-2 49831-28-9 159691-03-9 3749-36-8
3540-36-1 83568-11-0 16698-52-5
下游产品  0