4337-43-3

• 常用中文名：5-氯苯并[d]异噻唑-3-醇
• 常用英文名：5-Chloro-1,2-benzisothiazol-3(2H)-one
• CAS号：4337-43-3
• 分子式：C₇H₄ClNOS
• 分子量：185.63100
• 发布时间：2018-12-31 10:06:47
• 更新时间：2026-08-17 23:05:56
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名称

• 中文名: 5-氯-1,2-苯异噻唑-3(2H)-酮
• 英文名: 5-chloro-1,2-benzothiazol-3-one
• 中文别名: 5-氯苯并[D]异噻唑-3-醇; 5-氯-1,2-苯并二噻唑-3(2H)-酮; 5 - 氯-1,2 - 苯并异噻唑-3(2H) - 酮
• 英文别名: 5-Chloro-1,2-benzisothiazol-3(2H)-one,5-Chlorobenzisothiazolone; 5-chloro-1,2-benzisothiazol-3(2H)-one; 5-Chlor-3-oxo-2,3-dihydro-benzisothiazol; 5-chloro-1,2-benzisothiazolin-3-one; Einecs -1; 5-chloro-benz[d]isothiazol-3-one; 1,2-Benzisothiazol-3(2H)-one, 5-chloro; 5-chloro-1,2-benzothiazol-3(2h)-one; 1,2-Benzisothiazolin-3-one, 5-chloro; 5-chloro-2-benzisothiazolin-3-one; 5-Chlor-benz[d]isothiazol-3-on; EINECS 224-385-1; 5-Chlor-1,2-benzisothiazol-3-on; 1,2-Benzisothiazolin-3-one,5-chloro; 5-Chloro-1,2-benzisothiazolone; 5-chlorobenzo[d]isothiazol-3(2H)-one; 5-CHLORO-1,2-BENZISOTHIAZOL-3(2H)-ONE; 5-Chloro-1,2-benzisothiazolin-3-one; 5-chloro-benzo[d]isothiazol-3-one

物化性质

• 密度: 1.515g/cm3
• 熔点: 265-266ºC
• 分子式: C₇H₄ClNOS
• 分子量: 185.63100
• 精确质量: 184.97000
• PSA: 61.10000
• LogP: 2.24300
• 折射率: 1.669
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DE4168000 CHEMICAL NAME : 1,2-Benzisothiazolin-3-one, 5-chloro- CAS REGISTRY NUMBER : 4337-43-3 LAST UPDATED : 198709 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C7-H4-Cl-N-O-S MOLECULAR WEIGHT : 185.63 WISWESSER LINE NOTATION : T56 BSMVJ GG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 390 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,1301,1964

合成路线

256947-58-7 ~76% 4337-43-3

文献：Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012

19993-65-8 ~% 4337-43-3

文献：Miura, Yozo Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2850 - 2852

52948-10-4 ~% 4337-43-3

文献：Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012

19993-66-9 ~% 4337-43-3

文献：Miura, Yozo Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2850 - 2852

147-93-3 ~% 4337-43-3

文献：Hart et al. Journal of the Chemical Society, 1938 , p. 2114,2117

上下游产品

上游产品  3
19993-65-8 19993-66-9 147-93-3
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