924663-38-7

• 常用中文名：雷贝拉唑N-氧化物
• 常用英文名：Rabeprazole N-oxide
• CAS号：924663-38-7
• 分子式：C₁₈H₂₁N₃O₄S
• 分子量：375.442
• 发布时间：2018-09-21 07:04:50
• 更新时间：2024-01-12 08:48:23

名称

• 中文名: 雷贝拉唑N-氧化物
• 英文名: 2-[[4-(3-methoxypropoxy)-3-methyl-1-oxidopyridin-1-ium-2-yl]methylsulfinyl]-1H-benzimidazole
• 中文别名: 雷贝拉唑EP杂质D
• 英文别名: 2-[4-(3-methoxypropoxy)-3-methyl-1-oxypyridin-2-yl-methylsulfinyl]-1H-benzimidazole; 2-[[[4-(3-METHOXYPROPOXY)-3-METHYL-1-OXIDO-PYRIDIN-2-YL]METHYL]SULFINYL]-1H-BENZO[D]IMIDAZOLE; 2-{[4-(3-methoxypropoxy)-3-methyl-1-oxidopyridin-2-yl]methylsulfinyl}-1H-benzoimidazole; 2-[[[4-[3-methoxypropoxy]-3-methyl-2-pyridinyl]-methyl]sulfinyl]-1H-benzimidazole N-oxide; 2-[[[1-Oxide-4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; 2-[[[4-(3-Methoxypropoxy)-3-methyl-1-oxido-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; 2-[(4-(3-Methoxypropoxy)-3-methyl-pyridin-2-yl-1-oxide)methylsulfinyl]-1H-benzoimidazole; Rabeprazole N-Oxide; 2-[([4-(3-methoxypropoxy)-3-methyl-2-pyridinyl-1-oxide]methyl)-sulfinyl]-1H-benzimidazole; UNII:17Q1V00385; Rabeprazole Impurity 1

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 699.3±65.0 °C at 760 mmHg
• 分子式: C₁₈H₂₁N₃O₄S
• 分子量: 375.442
• 闪点: 376.7±34.3 °C
• 精确质量: 375.125275
• PSA: 109.72000
• LogP: -0.23
• 蒸汽压: 0.0±2.2 mmHg at 25°C
• 折射率: 1.648

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

924663-40-1 ~35% 924663-38-7

文献：Radl, Stanislav; Klecan, Ondrej; Havlicek, Jaroslav Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1447 - 1453

924663-39-8 ~% 924663-38-7

文献：Synthetic Communications, , vol. 37, # 17 p. 2861 - 2868

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