180272-28-0

• 常用中文名：索利那新N-氧化物
• 常用英文名：Solifenacin N-Oxide
• CAS号：180272-28-0
• 分子式：C₂₃H₂₆N₂O₃-
• 分子量：378.46400
• 发布时间：2017-08-07 10:53:15
• 更新时间：2026-07-20 01:42:08

名称

• 中文名: 索利那新N-氧化物
• 英文名: Solifenacin N-Oxide
• 中文别名: 索利那新杂质09; 索利那新杂质I(氮氧化物); N-氧化物,索非那新; 索非那新氧化物; 索非那新杂质I(索非那新N-氧化物); (R)-3-(((S)-1-苯基-1,2,3,4-四氢异喹啉-2-羰基)氧基)奎宁环-1-氧化物; 1-氧代-1-氮杂双环[2.2.2]辛-3-基1-苯基-3,4-二氢-2(1H)-异喹啉羧酸酯; 索利那新杂质I(索利那新N-氧化物); 索利那新氧化物杂质; 琥珀酸索利那新杂质I; 索利那氮氧化物; 索利那新杂质I; 索非那新杂质I; 索菲那新杂质1(索菲那新杂质I); 索利那新杂质一; 索利那新氮氧化合物; 索非那氮氧化物; 索非那杂质B; 索利那新琥珀酸盐杂质I; SOLIFENACIN 杂质I
• 英文别名: (1R,3R,4R)-3-((1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)oxy)quinuclidine 1-oxide; Solifenacin Impurity 1; Solifenacin Impurity I (N-Oxide); 1-Oxido-1-Azabicyclo[2.2.2]Oct-3-Yl 1-Phenyl-3,4-Dihydro-2(1H)-Isoquinolinecarboxylate; Solifenacin Impurity 1（Solifenacin Impurity I）; (3R)-3-[[(1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carbonyl]oxy]-1-azabicyclo[2.2.2]octane 1-oxide (solifenacin N-oxide); solifenacin succinate n-oxide; (R)-3-(((S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)oxy)quinuclidine 1-oxide; (1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecboxylic Acid (3R)-1-Oxido-1-azabicyclo[2.2.2]oct-3-yl Ester; SolifecinImpurityI-d5; Solifenacin N-oxideQ: What is Solifenacin N-oxide Q: What is the CAS Number of Solifenacin N-oxide Q: What is the storage condition of Solifenacin N-oxide Q: What e the applications of Solifenacin N-oxide; Solifenacin Impurity I; Solifenacin Succinate Impurity I; (3R)-3-[[(1S)-1-phenyl-3,4-dihydroisoquinoline- 2(1H)-carbonyl]oxy]-1-azabicyclo[2.2.2]octane 1-oxide; Solifenacin Succinate Impurity-1; SOLIFENACIN N-OXIDE IMPURITY; 2(1H)-Isoquinolinecboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl ester, (1S); Solifenacin Impurity I (Solifenacin N-Oxide); (1'S,3R)-3-[[(1'-phenyl-1',2',3',4'-tetrahydro-2'-isoquinolyl)carbonyl]oxy]quinuclidine 1-oxide; N-oxide-solifenacin; Solifenacin Impurity 9; Solina New Impurity I; Solifenacin impurity 5/Solifenacin Impurity I/Solifenacin N-Oxide/(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecboxylic Acid (3R)-1-Oxido-1 -azabicyclo[2.2.2]oct-3-yl Ester; (3R)-3-[[(1S)-1-phenyl-3,4-dihydroisquinoline-2(1H)-carbonyl]oxy]-1-azabicyclo[2.2.2]octane 1-oxide(solifenacin N oxide); (1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Oxido-1-azabicyclo[2.2.2]oct-3-yl Ester

物化性质

• 分子式: C₂₃H₂₆N₂O₃-
• 分子量: 378.46400
• 精确质量: 378.19400
• PSA: 55.84000
• LogP: 3.77420

合成路线

242478-37-1 ~83% 180272-28-0

文献：PHARMATHEN S.A.; KOFTIS, Theocharis, V.; SONI, Rohit, Ravikant; BODA, Bharat, Becharbhai; GHOTIKAR, Ravindra, Charudatta; PATEL, Vimal, Sudhirbhai Patent: WO2014/5601 A1, 2014 ; Location in patent: Page/Page column 10; 11 ;

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