145-14-2

• 常用中文名：4-孕烯-20-alpha-醇-3-酮
• 常用英文名：20(S)-Hydroxypregn-4-en-3-one
• CAS号：145-14-2
• 分子式：C₂₁H₃₂O₂
• 分子量：316.47800
• 发布时间：2019-01-03 18:09:47
• 更新时间：2026-07-14 15:14:39

名称

• 中文名: 4-孕烯-20-alpha-醇-3-酮
• 英文名: (20S)-20-hydroxypregn-4-en-3-one
• 中文别名: 孕酮杂质B(20(S) - 羟基黄体酮); 20Α-二氢孕酮; 黄体酮杂质2; 黄体酮杂质B (RRT≈0.68); 20Α-二氢孕酮-[13C3]; 孕酮杂质; 黄体酮杂质B /BP); 黄体酮杂质2(黄体酮杂质B); 20Α-羟基-4-孕烯-3-酮; 20Α-羟基黄体酮; 孕酮杂质B(20(S)-羟基孕酮); 20α-Dihydroprogesterone试剂; 黄体酮杂质B; 孕酮杂质B /BP); 孕酮杂质B; (20S)-二氢孕酮; 4-孕烯-20Α-醇-3-酮
• 英文别名: 20α-OH-Progesterone; 20α-Progerol; 20a-Dihydroprogesterone; 20-ALPHA-DIHYDROPROGESTERONE; BTX; 4-Pregnen-20α-ol-3-one; Progesterone Impurity B (20(S)-Hydroxy Progesterone); EINECS 205-649-5; 20α-Hydroxydihydroprogesterone; 4-Pregnen-3-one-20α-ol; progesterol-20-alpha; 4-PREGNEN-20-ALPHA-OL-3-ONE; 20alpha-Dihydroprogesterone; 20-alpha-hydroxydihydroprogesterone; 20-alpha-progerol; C04042; Progesterone Impurity 2(Progesterone Impurity B); Progesterol-20α; 20α-Hydroxy-4-pregnen-3-one, 20α-Hydroxyprogesterone; 4-pregnen-20A-ol-3-one; 20-ALPHA-HYDROXY-4-PREGNEN-3-ONE; 20-alpha-hydroxy-pregn-4-en-3-on; Pregn-4-ene-20α-ol-3-one; Δ4-Pregnen-20α-ol-3-one; Progesterone IMP B; Progesterone Impurity B; 20α-Dihydroprogesterone; 20α-Hydroxy-4-pregnen-3-one; 20α-OH-P; 20a-Hydroxypregn-4-en-3-one; 20α-Dihydroprogesterone-[2,3,C3]; dihydroprogesterone; (8S,9S,10R,13R,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; delta4-Pregnen-20alpha-ol-3-one; 4-PREGNEN-20ALPHA-OL-3-ON; 20.α.-Hydroxydihydroprogesterone; Δ4-Pregnene-20α-ol-3-one; (20s)-pregn-4-en-3-on; (8S,9S,10R,13S,14S,17S)-17-((S)-1-hydroxyethyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one; 20alpha-Hydroxypregn-4-en-3-one; 20α-Hydroxy-Δ4-pregnen-3-one; Pregn-4-en-3-one, 20-hydroxy-, (20S); (20s)-20-hydroxypregn-4-en-3-one; 20(s)-hydroxyprogesterone; 20-ALPHA-HYDROXYPROGESTERONE

物化性质

• 密度: 1.09g/cm3
• 沸点: 451.7ºC at 760mmHg
• 分子式: C₂₁H₃₂O₂
• 分子量: 316.47800
• 闪点: 192.4ºC
• 精确质量: 316.24000
• PSA: 37.30000
• LogP: 4.51530
• 蒸汽压: 4.65E-10mmHg at 25°C
• 折射率: 1.549
• 分子结构:

  1、 摩尔折射率：92.35

  2、 摩尔体积（cm³/mol）：290.0

  3、 等张比容（90.2K）：741.7

  4、 表面张力（dyne/cm）：42.7

  5、 极化率（10-24cm3）：36.61

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU5559900 CHEMICAL NAME : Pregn-4-en-3-one, 20-alpha-hydroxy- CAS REGISTRY NUMBER : 145-14-2 BEILSTEIN REFERENCE NO. : 2220567 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H32-O2 MOLECULAR WEIGHT : 316.53 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 40 mg/kg SEX/DURATION : female 10 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 10 mg/L REFERENCE : AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 127,151,1977

安全

• WGK德国: 3
• RTECS号: TU5559900

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