69226-06-8

• 常用中文名：2,2-DIETHYL-3-THIOMORPHOLINONE
• 常用英文名：2,2-DIETHYL-3-THIOMORPHOLINONE
• CAS号：69226-06-8
• 分子式：C₈H₁₅NOS
• 分子量：173.27600
• 发布时间：2016-02-18 19:31:59
• 更新时间：2024-01-09 12:08:21

名称

• 英文名: 2,2-diethylthiomorpholin-3-one
• 英文别名: 3-Thiomorpholinone,2-diethyl; 3-Thiomorpholinone,2,2-diethyl; 2,2-diethyl-thiomorpholin-3-one; 2,2-Diaethyl-thiomorpholin-3-on; 2,2-Diethyl-3-thiomorpholinone; 3-Oxo-2.2-diaethyl-thiomorpholin

物化性质

• 密度: 1.007g/cm3
• 沸点: 331.7ºC at 760 mmHg
• 分子式: C₈H₁₅NOS
• 分子量: 173.27600
• 闪点: 154.4ºC
• 精确质量: 173.08700
• PSA: 54.40000
• LogP: 1.73700
• 折射率: 1.477

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XM3054000 CHEMICAL NAME : 3-Thiomorpholinone, 2,2-diethyl- CAS REGISTRY NUMBER : 69226-06-8 BEILSTEIN REFERENCE NO. : 0119577 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C8-H15-N-O-S MOLECULAR WEIGHT : 173.30 WISWESSER LINE NOTATION : T6MV DSTJ C2 C2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,136,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 652 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,136,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 137 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,136,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,136,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 185 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,136,1963

合成路线

52988-77-9 ~% 69226-06-8

文献：Hoffmann-La Roche Patent: US2755278 , 1954 ;

91426-73-2 ~% 69226-06-8

文献：Hoffmann-La Roche Patent: US2755278 , 1954 ;

5456-23-5 ~% 69226-06-8

文献：Hoffmann-La Roche Patent: US2755278 , 1954 ;

67431-23-6 ~% 69226-06-8

文献：Hoffmann-La Roche Patent: US2755278 , 1954 ;

90647-45-3 ~% 69226-06-8

文献：Hoffmann-La Roche Patent: US2755278 , 1954 ;

98487-12-8 ~% 69226-06-8

文献：Skinner,G.S.; Macnair,R.N. Journal of Organic Chemistry, 1960 , vol. 25, p. 1164 - 1168

151-56-4 67431-23-6 ~% 69226-06-8

文献：Lehr,H. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 136 - 141

上下游产品

上游产品  5
52988-77-9 91426-73-2 5456-23-5 67431-23-6
151-56-4
下游产品  0