70058-19-4

• 常用中文名：(S)-2-(1-羟基丙-2-基)异吲哚啉-1,3-二酮
• 常用英文名：(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione
• CAS号：70058-19-4
• 分子式：C₁₁H₁₁NO₃
• 分子量：205.21000
• 发布时间：2018-10-08 21:53:16
• 更新时间：2024-01-09 17:25:34

名称

• 中文名: (S)-(+)-2-酞酰亚胺基-1-丙醇
• 英文名: 2-[(1s)-2-hydroxy-1-methylethyl]-1h-isoindole-1,3(2h)-dione
• 中文别名: 2-[(1s)-2-羟基-1-甲基乙基]-1h-异吲哚-1,3(2h)-二酮
• 英文别名: (S)-N-carboxylic acid ethyl ester-1-phenyl-1,2,3,4-tetrahydroisoquinoline; (S)-ethyl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate; 1(S)-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester; (S)-1,2,3,4-tetrahydro-1-phenyl-isoquinoline-2-carboxylic acid ethyl ester; (S)-2-phtalimidopropanol; (S)-(+)-N-Phthalylalaninol; (1'S)-N-(1'-hydroxyethyl-2'-methyl)-1H-isoindole-1,3(2H)-dione; (+)-(S)-2-(2-hydroxy-1-methylethyl)-1H-isoindole-1,3(2H)-dione; (1S)-ethyl 1-phenyl-1,2,3,4-tetrahydro-2-isoquinoline carboxylate; (S)-2-phthalimido-1-propanol; (S)-2-phthalimidopropanol; (1S)-1-phenyl-1,2,3,4-tetrahydro-isoquinoline-2-carboxylic acid ethyl ester; ETHYL (S)-1-PHENYL-1,2,3,4-TETRAHYDRO-2-ISOQUINOLINECARBOXYLATE

物化性质

• 密度: 1.348
• 沸点: 357ºC
• 熔点: 79-82ºC
• 分子式: C₁₁H₁₁NO₃
• 分子量: 205.21000
• 闪点: 170ºC
• 精确质量: 205.07400
• PSA: 57.61000
• LogP: 0.60130
• 储存条件: 2-8°C

合成路线

85-44-9 2749-11-3 ~99% 70058-19-4

文献：ELI LILLY AND COMPANY; COATES, David, Andrew; GILMOUR, Raymond; MARTIN, Jose, Alfredo; MARTIN DE LA NAVA, Eva, Maria Patent: WO2012/74761 A1, 2012 ; Location in patent: Page/Page column 17-18 ;

4192-28-3 ~99% 70058-19-4

文献：Casara, Patrick; Danzin, Charles; Metcalf, Brian; Jung, Michel Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2201 - 2208

85-44-9 6168-72-5 ~87% 70058-19-4

文献：Nisshin Flour Milling Co., Ltd. Patent: US4659833 A1, 1987 ; US 4659833 A

85-44-9 ~% 70058-19-4

文献：Casara, Patrick; Danzin, Charles; Metcalf, Brian; Jung, Michel Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2201 - 2208

2749-11-3 22509-74-6 ~74% 70058-19-4

文献：McArthur, Colin R.; Worster, Paul M.; Jiang, Ji-Long; Leznoff, Clifford Canadian Journal of Chemistry, 1982 , vol. 60, p. 1836 - 1841

885266-19-3 85-44-9 ~% 70058-19-4

文献：Edman, Karl; Ahlgren, Ragnhild; Bengtsson, Malena; Bladh, Hakan; Baeckstroem, Stefan; Dahmen, Jan; Henriksson, Krister; Hillertz, Per; Hulikal, Vijakumar; Jerre, Anders; Kinchin, Liz; Kase, Charlotte; Lepistoe, Matti; Mile, Irene; Nilsson, Stinabritt; Smailagic, Amir; Taylor, John; Tjoernebo, Ann; Wissler, Lisa; Hansson, Thomas Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 11 p. 2571 - 2577

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