60559-94-6

• 常用中文名：N'-cyano-N-(3-pyridyl)-N''-(t-butyl)guanidine
• 常用英文名：N'-cyano-N-(3-pyridyl)-N''-(t-butyl)guanidine
• CAS号：60559-94-6
• 分子式：C₁₁H₁₅N₅
• 分子量：217.27000
• 发布时间：2017-10-05 07:46:41
• 更新时间：2023-01-26 13:45:15

名称

• 英文名: 2-tert-butyl-1-cyano-3-pyridin-3-ylguanidine
• 英文别名: C11H15N5; P 1060; N-tert-butyl-N"-cyano-N'-3-pyridylguanidine

物化性质

• 密度: 1.08g/cm3
• 沸点: 332.8ºC at 760 mmHg
• 分子式: C₁₁H₁₅N₅
• 分子量: 217.27000
• 闪点: 155.1ºC
• 精确质量: 217.13300
• PSA: 73.10000
• LogP: 2.18258
• 折射率: 1.562

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : ME8945000 CHEMICAL NAME : Guanidine, 1-tert-butyl-2-cyano-3-(3-pyridyl)- CAS REGISTRY NUMBER : 60559-94-6 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H15-N5 MOLECULAR WEIGHT : 217.31 WISWESSER LINE NOTATION : T6NJ CMYUNCN&MX1&1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 278 mg/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,773,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,773,1978

合成路线

20837-86-9 40134-32-5 ~% 60559-94-6

文献：Leo Pharmaceutical Products Ltd. A/S Patent: US4057636 A1, 1977 ;

60572-68-1 ~% 60559-94-6

文献：Manley; Quast Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340

15268-31-2 ~% 60559-94-6

文献：Manley; Quast Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340

420-04-2 60572-83-0 ~% 60559-94-6

文献：Manley; Quast Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340