24676-80-0

• 常用中文名：Norscopolamine hydrochloride
• 常用英文名：Norscopolamine hydrochloride
• CAS号：24676-80-0
• 分子式：C₁₆H₂₀ClNO₄
• 分子量：325.78700
• 发布时间：2016-07-23 22:59:48
• 更新时间：2024-01-31 13:43:09

名称

• 英文名: Norscopolamine hydrochloride
• 英文别名: norscopolamine,hydrochloride; (S)-3-hydroxy-2-phenyl-propionic acid (1rN,2tH,4tH,5cN)-3-oxa-9-aza-tricyclo[3.3.1.02,4]non-7t-yl ester,hydrochloride; Norscopolamin-hydrochlorid

物化性质

• 沸点: 474.7ºC at 760mmHg
• 分子式: C₁₆H₂₀ClNO₄
• 分子量: 325.78700
• 闪点: 240.9ºC
• 精确质量: 325.10800
• PSA: 71.09000
• LogP: 1.70670
• 蒸汽压: 8.13E-10mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RD1575000 CHEMICAL NAME : 1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol, 6-beta,7-beta-epoxy-, (-)-tropate, hydrochloride CAS REGISTRY NUMBER : 24676-80-0 LAST UPDATED : 199109 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C16-H19-N-O4.Cl-H MOLECULAR WEIGHT : 325.82 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3020 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4230 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraduodenal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 860 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969

合成路线

114-49-8 ~78% 24676-80-0

文献：Banholzer; Pook Arzneimittel-Forschung/Drug Research, 1985 , vol. 35, # 1 A p. 217 - 228

上下游产品

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114-49-8
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30286-75-0